Avonex
Generic name: Interferon Beta-1a
Drug class:
Interferons
Usage of Avonex
Avonex is made from human proteins. Interferons help the body fight viral infections.
Avonex is used to treat relapsing multiple sclerosis (MS) in adults (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease).
Avonex will not cure MS, it will only decrease the frequency of relapse symptoms.
Avonex side effects
Get emergency medical help if you have signs of an allergic reaction to Avonex (hives, itching, anxiety, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Interferon beta-1a can cause life-threatening blood clots in the small blood vessels inside your organs, such as your brain or kidneys. Seek medical help right away if you have symptoms of this condition, such as a fever, tiredness, decreased urination, bruising, or nosebleeds.
Call your doctor at once if you have:
Common Avonex side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Avonex
You should not use Avonex if you are allergic to natural or recombinant interferon beta or albumin.
To make sure Avonex is safe for you, tell your doctor if you have:
Some brands of interferon beta-1a contain donated human plasma and may contain viruses or other infectious agents. Donated plasma is tested and treated to reduce the risk of contamination, but there is still a small possibility it could transmit disease. Ask your doctor about any possible risk.
Tell your doctor if you are pregnant or plan to become pregnant, or if you are breastfeeding.
Interferon beta-1a is not approved for use by anyone younger than 18 years old.
Relate drugs
- Actimmune
- Alferon N
- Avonex
- Avonex Pen
- Avonex Prefilled Syringe
- Betaseron
- Extavia
- Interferon alfa-n3
- Interferon beta-1a
- Interferon beta-1b
- Interferon gamma-1b
- Peginterferon beta-1a
- Plegridy
- Plegridy Pen
- Plegridy Pen Starter Pack
- Rebif
- Rebif Rebidose
- Rebif Rebidose Titration Pack
How to use Avonex
Usual Adult Dose for Multiple Sclerosis:
30 mcg IM once a week: titration dose to reduce the incidence and severity of influenza-like symptoms: Week 1: 7.5 mcg IM once a week Week 2: 15 mcg IM once a week Week 3: 22.5 mcg IM once a week Week 4+: 30 mcg IM once a week Use: For the treatment of patients with relapsing forms of multiple sclerosis to slow the accumulation of physical disability and decrease the frequency of clinical exacerbations. Patients with multiple sclerosis in whom efficacy has been demonstrated include patients who have experienced a first clinical episode and have MRI features consistent with multiple sclerosis
Warnings
Avonex can harm your liver. Call your doctor if you have symptoms such as nausea, loss of appetite, tiredness, confusion, easy bruising or bleeding, dark urine, clay-colored stools, or yellowing of your skin or eyes.
Some people have thoughts about suicide while using interferon beta-1a. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.
Before using Avonex, tell your doctor if you are allergic to any drugs, or if you have liver disease, a thyroid disorder, epilepsy or other seizure disorder, heart disease, chest pain (angina), congestive heart failure, a heart rhythm disorder, or a history of depression or suicidal behavior.
What other drugs will affect Avonex
Other drugs may interact with interferon beta-1a, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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