Azedra
Generic name: Iobenguane I-131
Drug class:
Therapeutic radiopharmaceuticals
Usage of Azedra
Azedra is a radiopharmaceutical (RAY dee oh far ma SOO tik al) medicine that is used to treat a certain type of adrenal gland tumor (pheochromocytoma).
Azedra is also used to treat a rare type of nerve cell tumor (paraganglioma) that can spread throughout the body.
Azedra is for use in adults and children who are at least 12 years old.
Azedra may also be used for purposes not listed in this medication guide.
Azedra side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Azedra may cause serious side effects. Call your doctor at once if you have:
Common side effects of Azedra may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Azedra
Tell your doctor if you have ever had:
Using Azedra may increase your risk of developing other cancers, such as leukemia. Ask your doctor about this risk.
You may need to have a negative pregnancy test before starting this treatment.
Azedra can harm an unborn baby if the mother or the father is receiving this medicine.
This medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because Azedra can harm an unborn baby.
Do not breast-feed while using this medicine, and for at least 80 days after your last dose.
Relate drugs
- Azedra
- Chromic phosphate p 32
- Iobenguane I-131
- Lutathera
- Lutetium Lu 177 dotatate
- Lutetium lu 177 vipivotide tetraxetan
- Metastron
- Phosphocol P-32
- Pluvicto
- Quadramet
- Radium Ra 223 dichloride
- Samarium sm 153 lexidronam
- Sodium phosphate p 32
- Strontium chloride sr 89
- Xofigo
How to use Azedra
Azedra is given as an infusion into a vein. A healthcare provider will give you this injection.
Azedra is usually given within 1 hour before the first in a series of 3 radiologic tests over 5 days. Two additional doses are then given, separated by at least 90 days.
You may be given other medication to help protect your thyroid gland from exposure to the radiation in Azedra. Keep using Azedra for as long as your doctor has prescribed.
Drink at least 2 liters of liquid on the day before you receive Azedra, and for 1 week afterward. Follow your doctor's instructions about the types of liquids you should drink. This medicine is radioactive and it can cause dangerous effects on your bladder if it is not properly eliminated from your body through urination.
Expect to urinate often during the first few days after your test. This will help rid your body of the radioactive materials.
Azedra can lower your blood cell counts. Your blood will need to be tested often. Your treatments may be delayed based on the results.
Your blood pressure and kidney function will also need to be checked often.
Warnings
Both men and women using Azedra should use effective birth control to prevent pregnancy. Azedra can harm an unborn baby if the mother or father is receiving this medicine.
If you are a woman, keep using birth control for at least 7 months after your last dose. If you are a man, keep using birth control for at least 4 months after your last dose.
What other drugs will affect Azedra
Some medicines can interfere with the quality of images produced by Azedra. Tell your doctor about all your current medicines and any you recently stopped using, especially:
This list is not complete and many other drugs may affect Azedra. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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