Azilsartan and chlorthalidone

Generic name: Azilsartan And Chlorthalidone
Brand names: Edarbyclor
Dosage form: oral tablet (40 mg-12.5 mg; 40 mg-25 mg)
Drug class: Angiotensin II inhibitors with thiazides

Usage of Azilsartan and chlorthalidone

Azilsartan is an angiotensin II receptor blocker (sometimes called an ARB). Chlorthalidone is a thiazide diuretic (water pill).

Azilsartan and chlorthalidone is a combination medicine used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Azilsartan and chlorthalidone may also be used for purposes not listed in this medication guide.

Azilsartan and chlorthalidone side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Azilsartan and chlorthalidone may cause serious side effects. Call your doctor at once if you have:

  • feeling like you might pass out;
  • little or no urination;
  • swelling, weight gain, feeling short of breath; or
  • signs of electrolyte imbalance--dry mouth, extreme thirst, weakness, drowsiness, restless feeling, confusion, increased or decreased urination, nausea and vomiting, constipation, muscle pain or weakness, fast heart rate, or seizure (convulsions).
  • Common side effects of azilsartan and chlorthalidone may include:

  • dizziness; or
  • feeling tired.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Azilsartan and chlorthalidone

    You should not use this medicine if you are allergic to azilsartan or chlorthalidone, or if you are unable to urinate.

    If you have diabetes, do not use azilsartan and chlorthalidone together with any medication that contains aliskiren (a blood pressure medicine).

    You may also need to avoid taking azilsartan and chlorthalidone with aliskiren if you have kidney disease.

    Tell your doctor if you have ever had:

  • liver or kidney disease;
  • gout;
  • an electrolyte imbalance (such as low levels of potassium in your blood);
  • heart disease or a stroke; or
  • if you are dehydrated.
  • Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

    Azilsartan and chlorthalidone can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. However, having high blood pressure during pregnancy may cause complications such as diabetes or eclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). Ask your doctor about a blood pressure medication that is safer to use during pregnancy.

    You should not breastfeed while you are using this medicine.

    Azilsartan and chlorthalidone is not approved for use by anyone younger than 18 years old.

    Relate drugs

    How to use Azilsartan and chlorthalidone

    Usual Adult Dose for Hypertension:

    Initial dose: Azilsartan 40 mg-Chlorthalidone 12.5 mg orally once a dayMaximum dose: Azilsartan 40 mg-Chlorthalidone 25 mg orally once a dayComments:-Correct any volume depletion prior to administration, especially in patients with impaired renal function or those on high diuretic doses.-May increase dose after 2 to 4 weeks as needed to achieve blood pressure goal.-Patients not controlled with azilsartan 80 mg monotherapy may achieve additional systolic and diastolic blood pressure reduction of 13 and 6 mmHg, respectively, when switched to the initial dose of this drug; patients not controlled with chlorthalidone 25 mg monotherapy may achieve additional systolic and diastolic blood pressure reduction of 10 and 7 mmHg, respectively, when switched to the initial dose of this drug.-This drug may be used as initial therapy if multiple drugs are likely needed to achieve blood pressure goals.

    Warnings

    You should not use azilsartan and chlorthalidone if you are unable to urinate.

    Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Ask your doctor about a blood pressure medication that is safer to use during pregnancy.

    If you have diabetes, do not use azilsartan and chlorthalidone together with any medication that contains aliskiren (a blood pressure medicine).

    What other drugs will affect Azilsartan and chlorthalidone

    Tell your doctor about all your other medicines, especially:

  • digoxin;
  • lithium;
  • a diuretic or "water pill"; or
  • other heart or blood pressure medicines.
  • This list is not complete. Other drugs may affect azilsartan and chlorthalidone, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Popular Keywords