Azithromycin

Generic name: Azithromycin
Drug class: Macrolides

Usage of Azithromycin

Azithromycin is an antibiotic that fights bacteria.

Azithromycin is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, eye infections, and sexually transmitted diseases.

Azithromycin may also be used for purposes not listed in this medication guide.

Azithromycin side effects

Get emergency medical help if you have signs of an allergic reaction to azithromycin: (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. This reaction may occur several weeks after you began using azithromycin.

Call your doctor at once if you have:

  • severe stomach pain, diarrhea that is watery or bloody;
  • fast or pounding heartbeats, fluttering in your chest, shortness of breath, and sudden dizziness (like you might pass out); or
  • liver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
  • Call your doctor right away if a baby taking azithromycin becomes irritable or vomits while eating or nursing.

    Older adults may be more likely to have side effects on heart rhythm, including a life-threatening fast heart rate.

    Common azithromycin side effects may include:

  • diarrhea;
  • nausea, vomiting, stomach pain; or
  • headache.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Azithromycin

    You should not use azithromycin if you are allergic to it, or if:

  • you have ever had jaundice or liver problems caused by taking azithromycin; or
  • you are allergic to similar drugs such as clarithromycin, erythromycin, or telithromycin.
  • To make sure azithromycin is safe for you, tell your doctor if you have ever had:

  • liver disease;
  • kidney disease;
  • myasthenia gravis;
  • a heart rhythm disorder;
  • low levels of potassium in your blood; or
  • long QT syndrome (in you or a family member).
  • This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

    It is not known whether azithromycin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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    How to use Azithromycin

    Take azithromycin exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. The dose and length of treatment may not be the same for every type of infection.

    You may take most forms of azithromycin with or without food.

    Take Zmax extended release liquid (oral suspension) on an empty stomach, at least 1 hour before or 2 hours after a meal.

    To use the oral suspension single dose packet: Open the packet and pour the medicine into 2 ounces of water. Stir this mixture and drink all of it right away. Do not save for later use. To make sure you get the entire dose, add 2 more ounces of water to the same glass, swirl gently and drink right away.

    Throw away any mixed Zmax oral suspension (extended release formulation) that has not been used within 12 hours. Throw away any immediate-release suspension that has not been used within 10 days.

    Shake the oral suspension (liquid) well just before you measure a dose. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

    Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may also increase your risk of further infection that is resistant to antibiotics. Azithromycin will not treat a viral infection such as the flu or a common cold.

    Store at room temperature away from moisture and heat.

    Warnings

    You should not use azithromycin if you have ever had jaundice or liver problems when you have previously taken this medicine.

    What other drugs will affect Azithromycin

    Tell your doctor about all your current medicines and any you start or stop using, especially:

  • digoxin; or
  • clarithromycin; or
  • a blood thinner - warfarin, Coumadin, Jantoven.
  • This list is not complete. Other drugs may interact with azithromycin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

    Popular FAQ

    There are several antibiotics that kill the common mouth bacteria that cause tooth infections. The best (first-line) antibiotics for tooth infection include: Amoxicillin, Penicillin, Cephalexin, Clindamycin, Azithromycin. Amoxicillin is often the first choice because it is widely effective and has the fewest gastrointestinal side effects. Continue reading

    Azithromycin will be in your system for around 15.5 days, after the last dose. Azithromycin has an elimination half-life of 68 hours. The prolonged terminal half-life is thought to be due to extensive uptake and subsequent release of drug from tissues. It takes around 5.5 x elimination half life's for a medicine to be out of your system. Continue reading

    Penicillin or amoxicillin are considered the best first-line treatments for Strep throat. According to the CDC (Centers for Disease Control and Prevention) “ There has never been a report of a clinical isolate of group A strep that is resistant to penicillin”. For people with a penicillin allergy, treat Strep throat with either a narrow-spectrum cephalosporin (such as cephalexin or cefadroxil), clindamycin, azithromycin, or clarithromycin. Note that resistance to azithromycin and clarithromycin has been reported. Continue reading

    A single dose of azithromycin 1 gram orally will cure genital chlamydia according to the CDC Guidelines for Sexually Transmitted Diseases but it will take approximately one week to work. You should not have sex during this time, otherwise you may infect your sexual partner with chlamydia. Continue reading

    There are several antibiotics that kill the common mouth bacteria that cause tooth infections. The best (first-line) antibiotics for tooth infection include: Amoxicillin, Penicillin, Cephalexin, Clindamycin, Azithromycin. Amoxicillin is often the first choice because it is widely effective and has the fewest gastrointestinal side effects. Continue reading

    Azithromycin will be in your system for around 15.5 days, after the last dose. Azithromycin has an elimination half-life of 68 hours. The prolonged terminal half-life is thought to be due to extensive uptake and subsequent release of drug from tissues. It takes around 5.5 x elimination half life's for a medicine to be out of your system. Continue reading

    Penicillin or amoxicillin are considered the best first-line treatments for Strep throat. According to the CDC (Centers for Disease Control and Prevention) “ There has never been a report of a clinical isolate of group A strep that is resistant to penicillin”. For people with a penicillin allergy, treat Strep throat with either a narrow-spectrum cephalosporin (such as cephalexin or cefadroxil), clindamycin, azithromycin, or clarithromycin. Note that resistance to azithromycin and clarithromycin has been reported. Continue reading

    A single dose of azithromycin 1 gram orally will cure genital chlamydia according to the CDC Guidelines for Sexually Transmitted Diseases but it will take approximately one week to work. You should not have sex during this time, otherwise you may infect your sexual partner with chlamydia. Continue reading

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