Aztreonam (Intravenous, Injection)

Generic name: Aztreonam
Drug class: Miscellaneous antibiotics

Usage of Aztreonam (Intravenous, Injection)

Aztreonam is an antibiotic that is used to treat infections caused by bacteria. It works by killing bacteria or preventing their growth.

Aztreonam is used to treat bacterial infections in many different parts of the body. It is sometimes given with other antibiotics. This medicine will not work for colds, flu, or other viral infections.

This medicine is available only with your doctor's prescription.

Aztreonam (Intravenous, Injection) side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common or rare

Black, tarry stools

blood in urine or stools

burning or itching of vagina

chest pain

chills

confusion

convulsions (seizures)

cough

dark urine

diarrhea

difficulty in breathing

discharge from vagina

discomfort, inflammation, or swelling at the injection site

dizziness

eye pain

fever

flu-like symptoms

general feeling of illness

headache

hives

light gray-colored stools

loss of appetite

numbness of tongue

pinpoint red spots on skin

seeing double

skin rash, redness, or itching

sore throat

unusual bleeding or bruising

unusual tiredness or weakness

yellow skin or eyes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

Abdominal or stomach cramps

altered sense of taste

bad breath

breast tenderness

burning or prickling feeling of skin

flushing

increased sweating

mouth ulcers

muscular aches

nasal congestion

nausea or vomiting

ringing, buzzing, or noise in ear

small, nonraised, round, purplish or red spots on skin

sneezing

trouble in sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Before taking Aztreonam (Intravenous, Injection)

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies have been done in children and have shown that aztreonam is effective in treating certain bacterial infections and that side effects in children are similar to those experienced by adults. Elevations of liver enzymes and reductions in white blood cell counts were seen in children who were given high doses of this medicine or who had more serious infections.

Geriatric

Aztreonam has been tested in a limited number of patients 65 years of age or older and has not been shown to cause different side effects or problems in older people than it does in younger adults.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Bupropion

Cholera Vaccine, Live

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Relate drugs

How to use Aztreonam (Intravenous, Injection)

To help clear up your infection completely, aztreonam must be given for the full time of treatment, even if you begin to feel better after a few days. Also, this medicine works best when there is a constant amount in the blood or urine. To help keep the amount constant, aztreonam must be given on a regular schedule.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For injection dosage form:

Adults and children 16 years of age and older: 1 to 2 grams injected slowly into a vein over a twenty- to sixty-minute period. This is repeated every six to twelve hours.

Children up to 16 years of age: Dosage is based on body weight and must be determined by your doctor.

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