Belladonna and opium

Generic name: Belladonna And Opium
Drug class: Narcotic analgesic combinations

Usage of Belladonna and opium

Belladonna and Opium suppositories are used to relieve moderate to severe pain caused by ureteral spasm. This medicine belongs to the group of medicines called narcotic analgesics (pain medicines).

When a narcotic is used for a long time, it may become habit-forming, causing mental or physical Dependence. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

This medicine is available only with your doctor's prescription.

Belladonna and opium side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Decrease in the frequency of urination

decrease in urine volume

difficulty in passing urine (dribbling)

painful urination

rapid pulse

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Change in consciousness

difficult or troubled breathing

dry mouth

fever

hot, dry, or flushed skin

irregular, fast or slow, or shallow breathing

loss of consciousness

pale or blue lips, fingernails, or skin

pinpoint pupils (black part of the eye)

shortness of breath

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Blurred vision

change in color vision

constipation

difficulty seeing at night

dizziness

drowsiness

hives or welts

increased sensitivity of the eyes to sunlight

itching skin

nausea or vomiting

redness of the skin

skin rash

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Before taking Belladonna and opium

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Use of belladonna and opium suppositories are not recommended in children 12 years of age and younger.

Geriatric

No information is available on the relationship of age to the effects of belladonna and opium suppositories in geriatric patients. However, elderly patients may be more sensitive to the effects of this medicine, which may require caution.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Nalmefene

Naltrexone

Potassium Citrate

Safinamide

Samidorphan

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Alfentanil

Alprazolam

Amantadine

Amphetamine

Benzhydrocodone

Benzphetamine

Bromazepam

Bromopride

Buprenorphine

Butorphanol

Calcium Oxybate

Cannabidiol

Cannabis

Carbinoxamine

Cetirizine

Citalopram

Clobazam

Clonazepam

Clopidogrel

Clozapine

Codeine

Daridorexant

Desmopressin

Desvenlafaxine

Dexmedetomidine

Dextroamphetamine

Dextromethorphan

Diazepam

Dihydrocodeine

Doxylamine

Duloxetine

Escitalopram

Esketamine

Fenfluramine

Fentanyl

Flibanserin

Fluoxetine

Fluvoxamine

Gabapentin

Gabapentin Enacarbil

Gepirone

Glucagon

Glycopyrrolate

Glycopyrronium Tosylate

Granisetron

Hydrocodone

Hydromorphone

Hydroxyamphetamine

Ketamine

Lacosamide

Lasmiditan

Lisdexamfetamine

Lithium

Lofexidine

Lorazepam

Loxapine

Magnesium Oxybate

Meclizine

Meperidine

Metaxalone

Methacholine

Methadone

Methamphetamine

Metoclopramide

Midazolam

Milnacipran

Mirtazapine

Morphine

Morphine Sulfate Liposome

Nalbuphine

Olanzapine

Ondansetron

Oxycodone

Oxymorphone

Ozanimod

Paroxetine

Pentazocine

Periciazine

Phenobarbital

Potassium Oxybate

Pregabalin

Primidone

Quetiapine

Remifentanil

Remimazolam

Revefenacin

RoPeginterferon Alfa-2b-njft

Scopolamine

Secretin Human

Sertraline

Sodium Oxybate

Sufentanil

Tapentadol

Tiotropium

Topiramate

Tramadol

Trazodone

Vilazodone

Vortioxetine

Zolpidem

Zuranolone

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acetophenazine

Chlorpromazine

Dixyrazine

Ethopropazine

Fluphenazine

Mesoridazine

Methdilazine

Methotrimeprazine

Perazine

Periciazine

Perphenazine

Pipotiazine

Prochlorperazine

Promazine

Promethazine

Propiomazine

Thiethylperazine

Thioridazine

Trifluoperazine

Triflupromazine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Relate drugs

How to use Belladonna and opium

Use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. This is especially important for elderly patients, who may be more sensitive to the effects of pain medicines. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence).

To use the suppository:

Never take rectal suppositories by mouth.

Wash your hands with soap and water before using this medicine.

Remove the foil or wrapper from the suppository before inserting it.

Moisten your finger and the suppository with water. Lie down on your side and use your finger to push the suppository well up into the rectum.

Keep lying down for about 15 minutes to keep the suppository from coming out before it melts. Then, wash your hands again.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For rectal dosage form (suppository):

For relief of moderate to severe pain:

Adults and teenagers—One suppository inserted into the rectum once or two times a day. The dose is usually not more than 4 suppositories per day, unless your doctor tells you otherwise.

Children up to 12 years of age—Use is not recommended.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate the suppositories.

Warnings

It is very important that your doctor check the progress of you or your child while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to use it.

This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose.

Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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