Belumosudil
Generic name: Belumosudil
Brand names: Rezurock
Dosage form: oral tablet (200 mg)
Drug class:
Selective immunosuppressants
Usage of Belumosudil
Belumosudil is used to treat chronic graft-versus-host disease after at least two other treatments did not work.
Belumosudil is for use in adults and children at least 12 years old.
Belumosudil may also be used for purposes not listed in this medication guide.
Belumosudil side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Belumosudil may cause serious side effects. Call your doctor at once if you have:
Common side effects of belumosudil may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Belumosudil
Tell your doctor if you have ever had liver or kidney problems.
You may need to have a negative pregnancy test before starting this treatment.
Both men and women using belumosudil should use effective birth control to prevent pregnancy. Belumosudil can harm an unborn baby if the mother or father is using this medicine.
Keep using birth control for at least 1 week after your last dose. Tell your doctor right away if a pregnancy occurs.
Pregnancy may be less likely to occur while the mother or the father is using this medicine. Both men and women should still use birth control to prevent pregnancy because the medicine can harm an unborn baby.
Do not breastfeed while using this medicine, and for at least 1 week after your last dose.
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How to use Belumosudil
Usual Adult Dose for Graft Versus Host Disease:
200 mg orally once a day until progression of chronic GVHD that requires new systemic therapyUse: For the treatment of adults with chronic graft-versus-host disease (chronic GVHD) after failure of at least 2 prior lines of systemic therapy
Usual Pediatric Dose for Graft Versus Host Disease:
200 mg orally once a day until progression of chronic GVHD that requires new systemic therapyUse: For the treatment of pediatric patients 12 years and older with chronic graft-versus-host disease (chronic GVHD) after failure of at least 2 prior lines of systemic therapy
Warnings
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
What other drugs will affect Belumosudil
Tell your doctor about all your current medicines. Many drugs can affect belumosudil, especially:
This list is not complete and many other drugs may affect belumosudil. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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