Benadryl

Generic name: Diphenhydramine

Usage of Benadryl

Benadryl is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Benadryl is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.

Benadryl is also used to treat motion sickness, to induce sleep, and to treat certain symptoms of Parkinson's disease.

Benadryl side effects

Get emergency medical help if you have signs of an allergic reaction to Benadryl: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Benadryl and call your doctor at once if you have:

  • pounding heartbeats or fluttering in your chest;
  • painful or difficult urination;
  • little or no urinating;
  • confusion, feeling like you might pass out; or
  • tightness in your neck or jaw, uncontrollable movements of your tongue.

    • Common Benadryl side effects may include:

  • dizziness, drowsiness, loss of coordination;
  • dry mouth, nose, or throat;
  • constipation, upset stomach;
  • dry eyes, blurred vision; or
  • day-time drowsiness or "hangover" feeling after night-time use.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Benadryl

    You should not use Benadryl if you are allergic to diphenhydramine.

    Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:

  • blockage in your digestive tract (stomach or intestines);
  • bladder obstruction or other urination problems;
  • a colostomy or ileostomy;
  • liver or kidney disease;
  • asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorder;
  • cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;
  • heart disease, low blood pressure;
  • glaucoma;
  • a thyroid disorder; or
  • if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

    • It is not known whether Benadryl will harm an unborn baby. Ask a doctor before using this medicine if you are pregnant.

    Diphenhydramine can pass into breast milk and may harm a nursing baby. Antihistamines may also slow breast milk production. Ask a doctor before using this medicine if you are breast-feeding.

    Older adults may be more likely to have side effects from this medicine.

    How to use Benadryl

    Use Benadryl exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cold or allergy medicine is usually taken only for a short time until your symptoms clear up.

    Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

    You should not use Benadryl to make a child sleepy.

    Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

    For motion sickness, take Benadryl 30 minutes before you will be in a situation that causes you motion sickness (such as a long car ride, airplane or boat travel, amusement park rides, etc). Continue taking Benadryl with meals and at bedtime for the rest of the time you will be in a motion-sickness situation.

    As a sleep aid, take Benadryl within 30 minutes before bedtime.

    Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

    This medication can affect the results of allergy skin tests. Tell any doctor who treats you that you are using Benadryl.

    Store at room temperature away from moisture and heat.

    Warnings

    You should not use Benadryl to make a child sleepy.

    When taking Benadryl, use caution driving, operating machinery, or performing other hazardous activities. Diphenhydramine may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

    Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking Benadryl.

    Do not give this medication to a child younger than 2 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

    What other drugs will affect Benadryl

    Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.

    Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking Benadryl with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

    Popular FAQ

    Benadryl should not be taken at the same time as cetirizine because it can increase side effects such as dizziness, drowsiness, and difficulty concentrating. Some people, especially the elderly or children, may also find their thinking, judgement, and coordination impaired. You should also not drink alcohol while taking either of these medications because it can make these side effects worse.

    The Hat Man is a fictional figure that started appearing on certain internet sites in the early 2000s that has recently been referred to as the “Benadryl Hat Man” after reports of people hallucinating and sighting him after overconsumption or abuse of Benadryl. Most of these reports have appeared on Reddit or the image-based bulletin site 4chan. Continue reading

    The maximum oral dose of diphenhydramine for adults is generally reported as 100mg for a single dose or no more than 300mg in 24 hours, but this can vary depending on what condition diphenhydramine is being used for, the salt of diphenhydramine used (there are two salts available in the US diphenhydramine citrate and diphenhydramine chloride), the age of the person, how much diphenhydramine they have tolerated before, and if they are on any interacting medications. Taking too much diphenhydramine can be fatal. Continue reading

    Mucinex products do not help to prevent or treat the COVID-19 virus itself, but might help relieve some of the symptoms of COVID, like chest congestion, cough, or headache. Select a product that targets only the symptoms you have. Continue reading

    Some vets might recommend these human over-the-counter (OTC) products, but at specific doses used only in dogs, as recommended by your vet. Do not use these products in dogs with glaucoma, prostate gland enlargement, and certain stomach, thyroid, seizure, or heart disorders. diphenhydramine (Benadryl) meclizine (Bonine) dimenhydrinate (Dramamine) Continue reading

    Increased blood pressure is not a typical side effect of diphenhydramine, a first-generation antihistamine that lowers the effects of histamines in your body. However, in rare cases, the drug may cause hypotension, or decreased blood pressure. This side effect is most likely to occur in people who are over the age of 60. Continue reading

    Benadryl should not be taken at the same time as cetirizine because it can increase side effects such as dizziness, drowsiness, and difficulty concentrating. Some people, especially the elderly or children, may also find their thinking, judgement, and coordination impaired. You should also not drink alcohol while taking either of these medications because it can make these side effects worse.

    The Hat Man is a fictional figure that started appearing on certain internet sites in the early 2000s that has recently been referred to as the “Benadryl Hat Man” after reports of people hallucinating and sighting him after overconsumption or abuse of Benadryl. Most of these reports have appeared on Reddit or the image-based bulletin site 4chan. Continue reading

    The maximum oral dose of diphenhydramine for adults is generally reported as 100mg for a single dose or no more than 300mg in 24 hours, but this can vary depending on what condition diphenhydramine is being used for, the salt of diphenhydramine used (there are two salts available in the US diphenhydramine citrate and diphenhydramine chloride), the age of the person, how much diphenhydramine they have tolerated before, and if they are on any interacting medications. Taking too much diphenhydramine can be fatal. Continue reading

    Mucinex products do not help to prevent or treat the COVID-19 virus itself, but might help relieve some of the symptoms of COVID, like chest congestion, cough, or headache. Select a product that targets only the symptoms you have. Continue reading

    Some vets might recommend these human over-the-counter (OTC) products, but at specific doses used only in dogs, as recommended by your vet. Do not use these products in dogs with glaucoma, prostate gland enlargement, and certain stomach, thyroid, seizure, or heart disorders. diphenhydramine (Benadryl) meclizine (Bonine) dimenhydrinate (Dramamine) Continue reading

    Increased blood pressure is not a typical side effect of diphenhydramine, a first-generation antihistamine that lowers the effects of histamines in your body. However, in rare cases, the drug may cause hypotension, or decreased blood pressure. This side effect is most likely to occur in people who are over the age of 60. Continue reading

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