Bevyxxa

Generic name: Betrixaban
Drug class: Factor Xa inhibitors

Usage of Bevyxxa

Bevyxxa blocks the activity of certain clotting substances in the blood.

Bevyxxa is a prescription medicine used to prevent blood clots in adults who have a serious illness and decreased ability to move. Blood clots are more likely when you are bedridden and you cannot move around.

It is not known if Bevyxxa is safe and effective in children or in people with artificial heart valves.

Bevyxxa side effects

Get emergency medical help if you have signs of an allergic reaction to Bevyxxa: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Also seek emergency medical attention if you have symptoms of a spinal blood clot: back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control.

Call your doctor at once if you have:

  • easy bruising or bleeding (nosebleeds, bleeding gums, heavy menstrual bleeding);
  • unexpected pain or swelling;
  • any bleeding that will not stop;
  • headache, dizziness, weakness, feeling like you might pass out;
  • urine that looks red, pink, or brown; or
  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

    • Common Bevyxxa side effect may include:

  • bleeding.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Bevyxxa

    You should not use Bevyxxa if you are allergic to betrixaban, or if you have active or uncontrolled bleeding.

    Bevyxxa may cause you to bleed more easily, especially if you have kidney disease or you use other medicines such as:

  • medicines to treat or prevent blood clots;
  • certain antidepressants, antibiotics, antifungal medicines, HIV medicines, or heart rhythm medicines; or
  • aspirin or an NSAID (nonsteroidal anti-inflammatory drug) such as ibuprofen (Advil, Motrin), naproxen (Aleve), Celecoxib, Diclofenac, indomethacin, or meloxicam.

    • Bevyxxa can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term paralysis, and may be more likely to occur if:

  • you have a genetic spinal defect;
  • you have a spinal catheter in place or if a catheter has been recently removed;
  • you have had spinal surgery, or repeated spinal taps or epidural anesthesia; or
  • you take an NSAID, or use other medicines to treat or prevent blood clots.

    • To make sure Bevyxxa is safe for you, tell your doctor if you have ever had:

  • liver or kidney disease;
  • an artificial heart valve; or
  • a bleeding or blood clotting disorder.

    • It is not known whether this medicine will harm an unborn baby. However, taking this medicine during pregnancy may increase the risk of bleeding while you are pregnant or during your delivery. Tell your doctor if you are pregnant or plan to become pregnant.

    It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

    Relate drugs

    How to use Bevyxxa

    Usual Adult Dose for Deep Vein Thrombosis -- Prophylaxis:

    Initial dose: 160 mg orally once Maintenance dose: 80 mg orally once a day with food Duration of therapy: 35 to 42 days Comments: -Safety and effectiveness have not been established in patients with prosthetic heart valves. Use: Prophylaxis of venous thromboembolism (VTE) in hospitalized patients with acute illness who are at risk of thromboembolic complications due to restricted mobility or other risk factors.

    Warnings

    Because Bevyxxa keeps your blood from clotting, this medicine can make it easier for you to bleed. Contact your doctor or seek emergency medical attention if you have unusual bruising or any bleeding that will not stop.

    Tell your doctor about all other medicines you use. Many drugs can further increase your risk of bleeding while you are taking Bevyxxa.

    Bevyxxa can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural), especially if you have a genetic spinal defect, if you have a spinal catheter in place, if you have a history of spinal surgery or repeated spinal taps, or if you are also using other drugs that can affect blood clotting. This type of blood clot can lead to long-term or permanent paralysis.

    Get emergency medical help if you have symptoms of a spinal cord blood clot such as back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control.

    What other drugs will affect Bevyxxa

    Tell your doctor about all your other medicines, especially:

  • cyclosporine;
  • St. John's wort;
  • an antibiotic;
  • an antidepressant;
  • antiviral medicine to treat HIV/AIDS;
  • heart or blood pressure medicine;
  • seizure medicine;
  • a blood-thinner - heparin, warfarin, or other medicines to treat or prevent blood clots; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

    • This list is not complete and many other drugs may interact with betrixaban. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

    Popular FAQ

    Bevyxxa is an oral capsule, once-daily Factor Xa inhibitor anticoagulant (blood thinner) used for the longer-term prevention (35 to 42 days) of venous thromboembolism (VTE). Venous thromboembolism occurs when a blood clot form in the vein. Bevyxxa is used for at-risk adults hospitalized for an acute medical illness, such as heart failure, stroke, infection and pulmonary disease, and that results in moderate or severe restricted mobility and other risk factors for VTE.

    Bevyxxa is an oral capsule, once-daily Factor Xa inhibitor anticoagulant (blood thinner) used for the longer-term prevention (35 to 42 days) of venous thromboembolism (VTE). Venous thromboembolism occurs when a blood clot form in the vein. Bevyxxa is used for at-risk adults hospitalized for an acute medical illness, such as heart failure, stroke, infection and pulmonary disease, and that results in moderate or severe restricted mobility and other risk factors for VTE.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Popular Keywords