Bexagliflozin

Generic name: Bexagliflozin
Brand names: Brenzavvy
Dosage form: oral tablet (20 mg)
Drug class: SGLT-2 inhibitors

Usage of Bexagliflozin

Bexagliflozin is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus (not for type 1 diabetes).

Bexagliflozin may also be used for purposes not listed in this medication guide.

Bexagliflozin side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Seek medical attention right away if you have signs of a genital infection (penis or vagina): burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, not feeling well. These symptoms may get worse quickly.

Bexagliflozin may cause serious side effects. Stop using bexagliflozin and call your doctor at once if you have:

nausea, vomiting, stomach pain; or

tiredness or trouble breathing.

Bexagliflozin may cause serious side effects. Call your doctor at once if you have:

signs of a bladder infection--pain or burning when you urinate, increased urination, blood in your urine, fever, pain in your pelvis or back;

low blood sugar--headache, weakness, drowsiness, confusion, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or

fever, feeling tired or uneasy, redness, swelling, pain or tenderness in your genital or anal area.

Common side effects of bexagliflozin may include:

increased or urgent need to urinate large amounts or at night;

pain and burning when you urinate; or

vaginal itching or discharge.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Bexagliflozin

You should not use bexagliflozin if you are allergic to it, or if you have:

severe kidney disease (or if you are on dialysis).

Bexagliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.

Tell your doctor if you have ever had:

type I diabetes or diabetic ketoacidosis;

low blood pressure;

bladder infections or other urination problems;

a diabetic foot ulcer or amputation;

circulation problems or nerve problems in your legs or feet;

problems with your pancreas, including surgery;

liver or kidney disease;

if you drink alcohol often;

if you also take blood pressure medication, including a diuretic ("water pill");

if you have a planned surgery; or

if you are eating less, there is a change in your diet, or you are on a low salt diet.

Follow your doctor's instructions about using this medicine if you are pregnant. Controlling diabetes is very important during pregnancy, and your dose needs may be different during each trimester.

You should not use bexagliflozin during the second or third trimester of pregnancy.

Do not breastfeed.

Relate drugs

How to use Bexagliflozin

Usual Adult Dose for Diabetes Type 2:

20 mg orally once daily in the morningComments:-Assess renal function before initiating this treatment and at periodic intervals during the treatment.-Not recommended for patients with an eGFR less than 30 mL/min/1.73 m2.-Assess and correct volume depletion before initiating treatment with this drug.Use: For the improvement of glycemic control in adults with type 2 diabetes mellitus

Warnings

You should not use bexagliflozin if you have severe kidney disease or diabetic ketoacidosis.

Bexagliflozin may increase your risk of lower leg amputation, especially if you have had a prior amputation, a foot ulcer, heart disease, circulation problems, or nerve damage.

You can easily become dehydrated while taking bexagliflozin, which can lead to severely low blood pressure or a serious electrolyte imbalance.

Bexagliflozin can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don't feel well.

What other drugs will affect Bexagliflozin

Tell your doctor about all your other medicines, especially:

diabetes medications.

This list is not complete. Other drugs may affect bexagliflozin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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