Bismuth subsalicylate, metronidazole, and tetracycline
Generic name: Bismuth Subsalicylate, Metronidazole, And Tetracycline
Brand names: Helidac
Dosage form: oral kit (262.4 mg-250 mg-500 mg)
Drug class:
H. pylori eradication agents
Usage of Bismuth subsalicylate, metronidazole, and tetracycline
Bismuth subsalicylate potassium, metronidazole, and tetracycline (Helidac) is a combination medicine used to treat peptic ulcer (duodenal ulcer) with Helicobacter pylori infection. Helidac is usually given together with another medicine to reduce stomach acid.
Helidac may also be used for purposes not listed in this medication guide.
Bismuth subsalicylate, metronidazole, and tetracycline side effects
Stop taking Helidac and get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Bismuth subsalicylate, metronidazole, and tetracycline may cause serious side effects. Call your doctor at once if you have:
Helidac may cause your tongue to become darker in color. It may also cause your stools to appear black in color. These are harmless and temporary side effects.
Common side effects of bismuth subsalicylate, metronidazole, and tetracycline may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Bismuth subsalicylate, metronidazole, and tetracycline
You should not use Helidac if you are allergic to bismuth subsalicylate potassium, metronidazole, or tetracycline, or if:
Tell your doctor if you have ever had:
Metronidazole has caused cancer in animal studies. It is not known whether this would occur in humans taking Helidac. Ask your doctor about the risk.
Do not use Helidac if you are pregnant. Tetracycline can cause permanent tooth discoloration and affect growth in the baby. Tell your doctor if you become pregnant.
Helidac can make birth control pills less effective. Ask your doctor about other birth control options such as an injection, implant, skin patch, vaginal ring, condom, diaphragm, cervical cap, or contraceptive sponge.
You should not breastfeed within 24 hours after using Helidac. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.
Not approved for use by anyone younger than 18 years old.
Relate drugs
- Amoxicillin and vonoprazan
- Amoxicillin, clarithromycin, and lansoprazole
- Amoxicillin, clarithromycin, and omeprazole
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- Bismuth subcitrate potassium, metronidazole, and tetracycline
- Bismuth subcitrate, metronidazole, and tetracycline
- Bismuth subsalicylate, metronidazole, and tetracycline
- Helidac
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- Omeclamox-Pak
- Omeprazole, amoxicillin, and rifabutin
- Omeprazole, clarithromycin, and amoxicillin
- Prevpac
- Pylera
- Talicia
- Triple Therapy
- Vonoprazan and amoxicillin
- Vonoprazan, amoxicillin, and clarithromycin
- Voquezna Dual Pak
- Voquezna Triple Pak
How to use Bismuth subsalicylate, metronidazole, and tetracycline
Usual Adult Dose for Helicobacter pylori Infection:
524.8 mg bismuth subsalicylate (chewable), metronidazole 250 mg, and tetracycline 500 mg orally four times daily for 14 days with meals and at bedtime. This therapy should be accompanied by a histamine-2 antagonist approved for the treatment of acute duodenal ulcer. The metronidazole tablet and the tetracycline capsule should be swallowed whole with a full glass of water (8 ounces).
Usual Pediatric Dose for Helicobacter pylori Infection:
8 years and older: Bismuth subsalicylate 524.8 to 525 mg-metronidazole 250 mg-tetracycline 500 mg orally 4 times a day (after meals and at bedtime)-Duration of therapy: 14 daysComment: An H(2) receptor antagonist approved to treat acute duodenal ulcer should be given with this drug.Use: Eradication of Helicobacter pylori infection in patients with active or a history of duodenal ulcer
Warnings
Do not drink alcohol or consume foods or medicines that contain propylene glycol while you are taking Helidac and for at least 3 days after you stop taking it.
Metronidazole has caused cancer in animal studies. It is not known whether this would occur in humans taking Helidac.
What other drugs will affect Bismuth subsalicylate, metronidazole, and tetracycline
Tell your doctor about all your current medicines. Many drugs can affect Helidac, especially:
This list is not complete and many other drugs may affect Helidac. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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