Black Haw
Generic name: Viburnum Prunifolium L.
Brand names: Black Haw, Blackhaw, Blackhaw Viburnum, Smooth Blackhaw, Smooth Blackhaw Viburnum, Stagbush, Sweet-haw
Usage of Black Haw
Antispasmodic activity
In vitro data
Properties associated with ethnobotanical use of V. prunifolium were investigated in vitro, specifically its spasmolytic effect on smooth muscle. The spontaneous contraction of rabbit jejunum was inhibited in a concentration-dependent manner by cumulative concentrations of V. prunifolium methanol extract, its ethanol and butanol fractions, and all 4 isolated iridoid glucosides in a similar but less potent manner than the beta-adrenergic agonist isoprenaline. Complete inhibition of spontaneous contraction was achieved with the highest concentrations, an effect that was reversed when the tissue was washed. The adrenergic antagonist propranolol antagonized the effect of all V. prunifolium components on the jejunum. Additionally, the same effects were observed on guinea pig trachea precontracted with Carbachol. However, washing the tissue did not reverse the relaxant effects imparted by the extracts. The most potent relaxation effects were observed with the ethanol fraction, followed by the butanol fraction, the methanol extract, the less polar iridoid 1 and iridoid 2, then finally the more polar iridoid 3 and iridoid 4. These data suggest the iridoids contribute to the spasmolytic effect of V. prunifolium and that the effect is mediated through the beta-adrenergic system.(Cometa 2009)
Dysmenorrhea
Animal and in vitro data
Relaxant activity in isolated uterine tissue has been demonstrated, possibly due to its scopoletin and amentoflavone constituents.(Evans 1942, Grote 1947, Jarboe 1966, Munch 1941)
Black Haw side effects
Black haw appears to be safe, but studies evaluating safety have not been performed.
Before taking Black Haw
Information regarding safety and efficacy in pregnancy and lactation is lacking.
Black haw has historically been used to prevent abortion and miscarriageBrinker 1998, Wilson 1886 Consultation with a medicinal herbalist or other licensed practitioner experienced in the use of black haw is recommended.
How to use Black Haw
There is no recent clinical evidence to provide dosing recommendations for black haw.
Consultation with a medicinal herbalist or other licensed practitioner experienced in the use of black haw is recommended.
Warnings
No data.
What other drugs will affect Black Haw
None well documented.
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