Brimonidine and brinzolamide ophthalmic

Generic name: Brimonidine And Brinzolamide Ophthalmic
Brand names: Simbrinza
Dosage form: ophthalmic suspension (0.2%-1%)
Drug class: Ophthalmic glaucoma agents

Usage of Brimonidine and brinzolamide ophthalmic

Brimonidine and Brinzolamide ophthalmic reduces the amount of fluid in the eye, which decreases pressure inside the eye.

Brimonidine and Brinzolamide ophthalmic (for the eyes) is a combination medicine used to treat open-angle glaucoma or ocular hypertension (high pressure inside the eye).

Brimonidine and brinzolamide ophthalmic may also be used for purposes not listed in this medication guide.

Brimonidine and brinzolamide ophthalmic side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

You may have other signs of allergic reaction that develop more slowly while using brimonidine and brinzolamide ophthalmic. Call your doctor if you have:

  • sudden liver failure--nausea, vomiting, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes), confusion, rapid weight gain, (especially in your midsection);
  • bone marrow suppression--sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing, pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating; or
  • severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

    • This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

  • blurred vision, tunnel vision, eye pain, or seeing halos around lights; or
  • eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection).

    • Common side effects of brimonidine and brinzolamide ophthalmic may include:

  • blurred vision;
  • mild itching, redness, or irritation of your eyes; or
  • dry mouth, unpleasant taste.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Brimonidine and brinzolamide ophthalmic

    You should not use brimonidine and brinzolamide ophthalmic if you are allergic to brimonidine or brinzolamide.

    Brimonidine and brinzolamide ophthalmic should not be given to a child younger than 2 years old.

    To make sure brimonidine and brinzolamide ophthalmic is safe for you, tell your doctor if you have:

  • kidney disease;
  • liver disease;
  • congestive heart failure, coronary artery disease, history of stroke or blood clot;
  • high or low blood pressure;
  • circulation problems, such as Raynaud's syndrome (numbness or cold feeling in your fingers or toes);
  • depression;
  • an allergy to sulfa drugs; or
  • narrow-angle glaucoma.

    • FDA pregnancy category C. It is not known whether brimonidine and brinzolamide ophthalmic will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

    It is not known whether brimonidine and brinzolamide ophthalmic passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

    Relate drugs

    How to use Brimonidine and brinzolamide ophthalmic

    Usual Adult Dose for Intraocular Hypertension:

    1 drop in the affected eye(s) 3 times per dayComments:-This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure.-If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.Use: To lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

    Usual Adult Dose for Glaucoma (Open Angle):

    1 drop in the affected eye(s) 3 times per dayComments:-This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure.-If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.Use: To lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

    Usual Pediatric Dose for Intraocular Hypertension:

    2 years or older:1 drop in the affected eye(s) 3 times per dayComments:-This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure.-If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.Use: To lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

    Usual Pediatric Dose for Glaucoma (Open Angle):

    2 years or older:1 drop in the affected eye(s) 3 times per dayComments:-This drug may be used concomitantly with other topical ophthalmic drugs to lower intraocular pressure.-If more than one topical ophthalmic drug is being used, the drugs should be administered at least 5 minutes apart.Use: To lower elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.

    Warnings

    Brimonidine and brinzolamide ophthalmic should not be given to a child younger than 2 years old.

    What other drugs will affect Brimonidine and brinzolamide ophthalmic

    Other drugs may interact with brimonidine and brinzolamide ophthalmic, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

    Popular Keywords