Brimonidine and timolol ophthalmic

Generic name: Brimonidine And Timolol Ophthalmic
Brand names: Combigan
Dosage form: ophthalmic solution (0.2%-0.5%)
Drug class: Ophthalmic glaucoma agents

Usage of Brimonidine and timolol ophthalmic

Brimonidine reduces the amount of fluid in the eye, which decreases pressure inside the eye.

Timolol is a beta-blocker that also reduces pressure inside the eye.

Brimonidine and timolol ophthalmic (for the eyes) is used to treat open-angle glaucoma or ocular hypertension (high pressure inside the eye).

Brimonidine and timolol ophthalmic may also be used for purposes not listed in this medication guide.

Brimonidine and timolol ophthalmic side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Brimonidine and timolol ophthalmic may cause serious side effects. Call your doctor at once if you have:

slow or uneven heart rate;

pounding heartbeats or fluttering in your chest;

shallow breathing, feeling like you might pass out;

severe swelling, redness, or discomfort in or around your eye;

eye pain or increased watering; or

numbness or tingly feeling in your hands or feet.

Common side effects of brimonidine and timolol ophthalmic may include:

drowsiness, tired feeling;

mild itching, redness, or irritation of your eyes; or

mild stinging or burning when using the eye drops.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Brimonidine and timolol ophthalmic

You should not use brimonidine and timolol ophthalmic if you are allergic to it, or if you have:

a history of asthma or chronic obstructive pulmonary disease (COPD); or

a serious heart condition such as "AV block," severe heart failure, or slow heartbeats that have caused you to faint.

To make sure brimonidine and timolol ophthalmic is safe for you, tell your doctor if you have:

congestive heart failure, coronary artery disease, history of stroke or blood clot;

high or low blood pressure, circulation problems (such as Raynaud's syndrome);

depression;

diabetes (using brimonidine and timolol ophthalmic may make it harder for you to tell when you have low blood sugar);

a thyroid disorder;

any allergies;

myasthenia gravis; or

a history of glaucoma or increased pressure inside your eye.

FDA pregnancy category C. It is not known whether brimonidine and timolol ophthalmic will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Timolol ophthalmic can pass into breast milk and may harm a nursing baby. You should not breast-feed while using brimonidine and timolol ophthalmic.

Do not give this medicine to a child without medical advice.

Relate drugs

How to use Brimonidine and timolol ophthalmic

Usual Adult Dose for Glaucoma:

1 drop in the affected eye(s) twice per day, approximately 12 hours apartComments:-If more than one topical ophthalmic drug is being used, the different drugs should be instilled at least 5 minutes apart.Use: To lower elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP

Usual Adult Dose for Intraocular Hypertension:

Usual Pediatric Dose for Glaucoma:

2 years or older:1 drop in the affected eye(s) twice per day, approximately 12 hours apartComments:-If more than one topical ophthalmic drug is being used, the different drugs should be instilled at least 5 minutes apart.Use: To lower elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP

Usual Pediatric Dose for Intraocular Hypertension:

Warnings

You should not use brimonidine and timolol ophthalmic if you have a history of asthma or chronic obstructive pulmonary disease (COPD), or a serious heart condition such as "AV block," severe heart failure, or slow heartbeats that have caused you to faint.

Brimonidine and timolol ophthalmic should not be given to a child younger than 2 years old.

What other drugs will affect Brimonidine and timolol ophthalmic

Using brimonidine and timolol ophthalmic with other drugs that make you sleepy or slow your breathing can increase these effects. Ask your doctor before using brimonidine and timolol ophthalmic with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with brimonidine and timolol ophthalmic, especially:

digoxin, digitalis;

reserpine;

an antidepressant--amitriptyline, Bupropion, clomipramine, desipramine, doxepin, duloxetine, fluoxetine, imipramine, nortriptyline, paroxetine;

an MAO inhibitor--isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, tranylcypromine;

a beta blocker--atenolol, carvedilol, labetalol, metoprolol, nadolol, nebivolol, propranolol, sotalol, and others; or

heart or blood pressure medicine--amlodipine, diltiazem, methyldopa, nifedipine, quinidine, verapamil, and others.

This list is not complete. Other drugs may interact with brimonidine and timolol ophthalmic, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.