Brompheniramine, chlorpheniramine, methscopolamine, phenylephrine, and pseudoephedrine

Generic name: Brompheniramine, Chlorpheniramine, Methscopolamine, Phenylephrine, And Pseudoephedrine
Brand names: SymPak II
Dosage form: oral kit (-)
Drug class: Upper respiratory combinations

Usage of Brompheniramine, chlorpheniramine, methscopolamine, phenylephrine, and pseudoephedrine

Brompheniramine, Chlorpheniramine, and methscopolamine are antihistamines that reduce the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine and pseudoephedrine are decongestants that shrink blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Brompheniramine, chlorpheniramine, methscopolamine, phenylephrine, and pseudoephedrine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, and sinus congestion caused by allergies, the common cold, or the flu.

This combination medicine may also be used for purposes not listed in this medication guide.

Brompheniramine, chlorpheniramine, methscopolamine, phenylephrine, and pseudoephedrine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

  • pounding heartbeats or fluttering in your chest;
  • shortness of breath;
  • mood changes;
  • tremor, seizure (convulsions);
  • double vision;
  • ongoing diarrhea or vomiting;
  • little or no urination;
  • easy bruising or bleeding, unusual weakness; or
  • high blood pressure--severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety.
  • Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

    Common side effects of brompheniramine, chlorpheniramine, methscopolamine, phenylephrine, and pseudoephedrine may include:

  • headache, dizziness, drowsiness;
  • dry mouth, nose, or throat;
  • tingly feeling;
  • nausea, bloating, constipation;
  • blurred vision;
  • feeling nervous or restless;
  • sleep problems (insomnia); or
  • decreased sweating.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Brompheniramine, chlorpheniramine, methscopolamine, phenylephrine, and pseudoephedrine

    Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

    You should not use this medicine if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate.

    To make sure this medicine is safe for you, tell your doctor if you have:

  • asthma or COPD;
  • high blood pressure, heart disease, coronary artery disease;
  • glaucoma;
  • an overactive thyroid;
  • diabetes;
  • liver or kidney disease;
  • epilepsy or other seizure disorder;
  • cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;
  • enlarged prostate or urination problems;
  • low blood pressure;
  • pheochromocytoma (an adrenal gland tumor); or
  • if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).
  • It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

    This medicine can pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Tell your doctor if you are breast-feeding a baby.

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    How to use Brompheniramine, chlorpheniramine, methscopolamine, phenylephrine, and pseudoephedrine

    Usual Adult Dose for Nasal Congestion:

    Brompheniramine/chlorpheniramine/methscopolamine/phenylephrine/pseudoephedrine oral kit:1 AM tablet orally in the morning and 1 PM tablet orally in the evening.

    Usual Pediatric Dose for Nasal Congestion:

    Brompheniramine/chlorpheniramine/methscopolamine/phenylephrine/pseudoephedrine oral kit:6 to 11 years: 1 AM tablet orally in the morning and 1/2 PM tablet orally in the evening.12 years or older: 1 AM tablet orally in the morning and 1 PM tablet orally in the evening.

    Warnings

    Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

    You should not use antihistamine medication to make a child sleepy.

    What other drugs will affect Brompheniramine, chlorpheniramine, methscopolamine, phenylephrine, and pseudoephedrine

    Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.

    Taking brompheniramine, chlorpheniramine, methscopolamine, phenylephrine, and pseudoephedrine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking this medicine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

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