Bupivacaine liposome
Generic name: Bupivacaine Liposome
Brand names: Exparel
Dosage form: injectable suspension (1.3% (13.3 mg/mL))
Drug class:
Local injectable anesthetics
Usage of Bupivacaine liposome
Bupivacaine is an anesthetic (numbing medicine) that blocks nerve impulses in your body.
Bupivacaine liposome is used as a local (in only one area) anesthetic to numb an area of your body for a minor surgery such as bunion removal or hemorrhoid surgery.
Bupivacine liposome is also used as a nerve block after surgery on your shoulder or upper arm, to provide pain relief to the area.
Bupivacaine may also be used for purposes not listed in this medication guide.
Bupivacaine liposome side effects
Get emergency medical help if you have signs of an allergic reaction: hives, red rash, itching; sneezing, difficulty breathing; severe dizziness, vomiting; swelling of your face, lips, tongue, or throat.
You will be watched closely after receiving bupivacaine liposome, to make sure you do not have a reaction to the medicine. Tell your caregivers at once if you have any of these signs of a serious side effect:
You may still feel numb or be unable to move the numbed area for up to 5 days after you are treated with bupivacaine liposome.
Common side effects include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Bupivacaine liposome
You should not be treated with bupivacaine if you are allergic to it.
Tell your doctor if you have ever had:
It is not known whether bupivacaine liposome will harm an unborn baby. Tell your doctor if you are pregnant.
It may not be safe to breast-feed a baby while you are using this medicine. Ask your doctor about any risks.
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How to use Bupivacaine liposome
Usual Adult Dose for Pain:
Local Analgesia via Infiltration: -Dose will be dependent on size of surgical site, volume required to cover area, and individual patient factors that may impact the safety of an amide local anesthetic. -Maximum infiltration dose: 266 mg (20 mL) Regional Analgesia via Interscalene Branchial Plexus Nerve Block:-Based upon study of patients undergoing total shoulder arthroplasty or rotator cuff repair: 133 mg (10 mg)Maximum dose for interscalene brachial plexus nerve block: 133 mg (10 mg)Comments:-This drug has not been evaluated for the following uses and, therefore, is not recommended for epidural, intrathecal, regional nerve blocks other than interscalene brachial plexus nerve block, and intravascular or intra-articular use. -Different formulations of bupivacaine are not bioequivalent. Uses: For single-dose infiltration to produce postsurgical local analgesia and as an interscalene brachial plexus nerve block to produce postsurgical regional analgesia.
Warnings
You may still feel numb or be unable to move the numbed area for up to 5 days after you are treated with bupivacaine liposome.
What other drugs will affect Bupivacaine liposome
Other drugs may affect bupivacaine liposome, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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