Byvalson

Generic name: Nebivolol And Valsartan
Drug class: Miscellaneous antihypertensive combinations

Usage of Byvalson

Byvalson is a combination medicine used to treat high blood pressure (hypertension) in adults. Lowering blood pressure may lower your risk of a stroke or heart attack.

Byvalson is sometimes given together with other blood pressure medications.

Byvalson contains a combination of nebivolol and valsartan. Nebivolol is a beta-blocker that affects the heart and circulation (blood flow through arteries and veins).

Valsartan is an angiotensin II receptor antagonist. Valsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Byvalson side effects

Get emergency medical help if you have signs of an allergic reaction to Byvalson: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Byvalson may cause serious side effects. Call your doctor at once if you have:

  • feeling like you might pass out;
  • very slow heartbeats;
  • low blood sugar - headache, hunger, weakness, sweating, confusion, irritability, dizziness, fast heart rate, or feeling jittery;
  • heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;
  • heart problems - swelling, rapid weight gain, feeling short of breath;
  • kidney problems - swelling, urinating less, feeling tired or short of breath; or
  • high blood potassium - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.
  • Common Byvalson side effects may include:

  • slow heartbeats.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Byvalson

    You should not use Byvalson if you are allergic to nebivolol or valsartan, or if you have:

  • a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker);
  • severe heart failure (that required you to be in the hospital or take certain medicines);
  • very low heartbeats (severe bradycardia); or
  • severe liver disease.
  • If you have diabetes, do not use Byvalson with any medication that contains aliskiren (a blood pressure medicine).

    You may also need to avoid taking Byvalson with aliskiren if you have kidney disease.

    To make sure Byvalson is safe for you, tell your doctor if you have ever had:

  • low blood pressure;
  • heart problems;
  • asthma or lung disease;
  • diabetes;
  • thyroid disorder;
  • blood flow problems to your feet and legs (peripheral vascular disease);
  • pheochromocytoma (tumor of the adrenal gland);
  • a severe allergic reaction to any blood pressure medication;
  • if you are on a low-salt diet;
  • if you plan to have surgery with general anesthesia;
  • liver disease; or
  • kidney disease (or if you are on dialysis).
  • Do not use Byvalson if you are pregnant. Stop using this medicine and tell your doctor right away if you become pregnant. Nebivolol and valsartan can cause injury or death to the unborn baby if you use the medicine during your second or third trimester.

    Do not breastfeed.

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    How to use Byvalson

    Usual Adult Dose for Hypertension:

    1 tablet orally daily with or without food Comments: -Maximum antihypertensive effects are attained within 2 to 4 weeks. -Increasing the dose does not result in any meaningful further blood pressure reduction.

    Warnings

    Do not use Byvalson if you are pregnant. Stop using and tell your doctor right away if you become pregnant. Valsartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

    If you have diabetes, do not use Byvalson together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

    What other drugs will affect Byvalson

    Tell your doctor about all your current medicines. Many drugs can affect Byvalson, especially:

  • cyclosporine;
  • fluoxetine;
  • lithium;
  • rifampin;
  • ritonavir;
  • a diuretic or "water pill";
  • other heart or blood pressure medicines; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs) - aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.
  • This list is not complete and many other drugs may interact with nebivolol and valsartan. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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