Cabazitaxel
Generic name: Cabazitaxel
Brand names: Jevtana
Dosage form: intravenous solution (60 mg/1.5 mL)
Drug class:
Mitotic inhibitors
Usage of Cabazitaxel
Cabazitaxel is used together with prednisone to treat prostate cancer that has spread to other parts of the body (metastatic).
Cabazitaxel is given after other cancer medicines have stopped working.
Cabazitaxel may also be used for purposes not listed in this medication guide.
Cabazitaxel side effects
Cabazitaxel can cause a serious allergic Reaction. Get emergency medical help if you have signs of an allergic reaction: hives, rash or skin redness; chest tightness or trouble breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.
Cabazitaxel can cause serious or fatal side effects. Call your doctor at once if you have:
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects of cabazitaxel may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Cabazitaxel
You should not use cabazitaxel if you are allergic to cabazitaxel, or if you have:
Tell your doctor if you have ever HAD:
Although not for use by women, cabazitaxel can cause birth defects in a baby if the father is using this medicine.
Use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose. Tell your doctor at once if a pregnancy occurs during this time.
This medicine may affect fertility (your ability to have children). However, it is important to use birth control to prevent pregnancy because cabazitaxel can harm an unborn baby.
Relate drugs
- Abraxane
- Cabazitaxel
- Docefrez
- Docetaxel
- Eribulin
- Etopophos
- Etoposide
- Etoposide (Intravenous)
- Etoposide (Oral)
- Etoposide injection
- Etoposide phosphate
- Halaven
- Ixabepilone
- Ixempra
- Jevtana
- Marqibo
- Navelbine
- Nov-Onxol
- Oncovin
- Onxol
- Paclitaxel
- Paclitaxel Novaplus
- Paclitaxel protein-bound
- Taxol
- Taxotere
- Teniposide
- Toposar injection
- Velban
- Vepesid (Etoposide Intravenous)
- Vepesid (Etoposide Oral)
- Vinblastine
- Vincasar PFS
- Vincristine
- Vincristine liposome
- Vinorelbine
- Vumon
How to use Cabazitaxel
Usual Adult Dose for Prostate Cancer:
20 mg/m2 IV over one-hour every three weeks-Some patients may received a dose of 25 mg/m2 every three weeksComments:-In selected patients, the dose may be increased to 25 mg/m2; primary prophylaxis with G-CSF is recommended in these patients. -Use in combination with oral prednisone 10 mg once a day.-Dose is based on calculation of the Body Surface Area (BSA).-Give premedication regimen at least 30 minutes prior to each administration, including antiemetics prophylaxis as needed.-Ensure adequate hydration throughout treatment.Use: In combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer previously treated with a docetaxel-containing treatment regimen
Warnings
Cabazitaxel affects your immune system. You may get infections more easily, even serious or fatal infections, especially if you are 65 or older. Call your doctor if you have a fever, muscle pain, cough, diarrhea, or pain or burning when you urinate.
A serious allergic reaction may occur during the injection. Tell your caregivers right away if you have a rash or skin redness, chest tightness or trouble breathing, swelling in your face, or if you feel like you might pass out.
Tell your doctor if you have other symptoms of serious side effects: severe stomach pain, blood in your urine or stools, little or no urinating, chest pain, or shortness of breath.
What other drugs will affect Cabazitaxel
Sometimes it is not safe to use certain medications at the SAMe time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Other drugs may affect cabazitaxel, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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