Calcium chloride/dextrose/hetastarch/magnesium chloride/potassium chloride/sodium chloride/sodium lactate

Generic name: Calcium Chloride/dextrose/hetastarch/magnesium Chloride/potassium Chloride/sodium Chloride/sodium Lactate
Drug class: Plasma expanders

Usage of Calcium chloride/dextrose/hetastarch/magnesium chloride/potassium chloride/sodium chloride/sodium lactate

Hextend® injection is used to treat low blood volume (hypovolemia) when other treatment is not available.

This medicine is to be given only by or under the supervision of your doctor.

Calcium chloride/dextrose/hetastarch/magnesium chloride/potassium chloride/sodium chloride/sodium lactate side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

  • Bloody or cloudy urine
  • blue lips and fingernails
  • blurred vision
  • chest pain, discomfort, or tightness
  • confusion
  • cough
  • coughing that sometime produces a pink frothy sputum
  • decreased urine output
  • difficulty swallowing
  • dilated neck veins
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • drowsiness
  • fainting
  • fast, slow, or irregular heartbeat or pulse
  • fever
  • hives, itching, skin rash
  • increased sweating
  • large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • muscle tremors
  • nausea
  • noisy breathing
  • no blood pressure or pulse
  • pale skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rapid shallow breathing
  • restlessness
  • sneezing
  • stomach cramps
  • stopping of the heart
  • sudden increase or decrease in the amount of urine
  • sweating
  • swelling around the eyes
  • swelling in the legs and ankles
  • swelling of the face, fingers, feet, or lower legs
  • unconsciousness
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • weight gain

    • Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

    Incidence not known

  • Chills
  • diarrhea
  • general feeling of discomfort or illness
  • headache
  • joint pain
  • muscle aches and pains
  • runny nose
  • shivering
  • sore throat
  • tingling of the feet
  • trouble sleeping
  • unusual weight gain or loss
  • vomiting

    • Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

    Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

    Before taking Calcium chloride/dextrose/hetastarch/magnesium chloride/potassium chloride/sodium chloride/sodium lactate

    In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

    Allergies

    Tell your doctor if you have ever had any unusual or allergic Reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

    Pediatric

    Appropriate studies on the relationship of age to the effects of Hextend® injection have not been performed in the pediatric population. Safety and efficacy have not been established.

    Geriatric

    Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Hextend® injection in the elderly. However, elderly patients are more sensitive to the effects of this medicine than younger adults and are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

    Breast Feeding

    Sodium ChlorideMagnesium

    Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

    Sodium LactateDextrosePotassiumCalcium

    There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

    Interactions with Medicines

    Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

    Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Eplerenone

    • Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Alacepril
  • Amiloride
  • Baloxavir Marboxil
  • Benazepril
  • Bictegravir
  • Canrenoate
  • Captopril
  • Cilazapril
  • Delapril
  • Digoxin
  • Eltrombopag
  • Erdafitinib
  • Fosinopril
  • Imidapril
  • Indomethacin
  • Lisinopril
  • Moexipril
  • Pentopril
  • Perindopril
  • Quinapril
  • Raltegravir
  • Ramipril
  • Sparsentan
  • Spirapril
  • Spironolactone
  • Temocapril
  • Trandolapril
  • Triamterene
  • Zofenopril

    • Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Chlorothiazide
  • Delafloxacin
  • Felodipine
  • Isradipine
  • Licorice
  • Nicardipine
  • Strontium Ranelate

    • Interactions with Food/Tobacco/Alcohol

    Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

    Other Medical Problems

    The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Alkalosis (high pH levels in the blood) or
  • Allergy to corn or
  • Diabetes or
  • Heart or blood vessel disease or
  • Hyperkalemia (high potassium levels in the blood) or
  • Kidney disease, severe—Use with caution. May make these conditions worse.
  • Heart bypass—May increase the risk for bleeding in patients undergoing this surgery.
  • Infection (eg, sepsis), severe or
  • Surgery or
  • Trauma—Use with caution. May increase the risk for serious kidney problems.
  • Leukapheresis—Use in not recommended in patients undergoing this procedure.
  • Liver disease, severe—Use with caution. May increase the risk for serious side effects.

    • Relate drugs

    How to use Calcium chloride/dextrose/hetastarch/magnesium chloride/potassium chloride/sodium chloride/sodium lactate

    A nurse or other trained health professional will give you this medicine in a medical facility. It is given as a needle placed into one of your veins.

    Warnings

    It is very important that your doctor check your progress closely while receiving the medicine to make sure it is working properly. Blood and urine tests are needed to check for unwanted effects.

    Call your doctor right away if you have bloody or cloudy urine, difficult or painful urination, sudden increase or decrease in the amount of urine, or swelling of the face, feet, or lower legs. These may be symptoms of a serious kidney problem.

    This medicine may cause a serious allergic reaction, called anaphylaxis, which can be life-threatening and requires immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing or swallowing, or any swelling of your hands, face, or mouth after receiving this medicine.

    Check with your doctor right away if you have black, tarry stools, blood in the urine or stools, headache, dizziness, or weakness, pain, swelling, or discomfort in a joint, pinpoint red spots on your skin, unusual nosebleeds, or any unusual bleeding or bruising.

    Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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