Candesartan

Generic name: Candesartan
Brand names: Atacand
Dosage form: oral tablet (16 mg; 32 mg; 4 mg; 8 mg)
Drug class: Angiotensin receptor blockers

Usage of Candesartan

Candesartan is an angiotensin II receptor blocker (sometimes called an ARB).

Candesartan is used to treat high blood pressure (hypertension) in adults and children who are at least 1 year old. Lowering blood pressure may lower your risk of a stroke or heart attack.

Candesartan is also used in adults to treat certain types of heart failure and lower your risk of death or needing to be hospitalized for heart damage.

Candesartan may also be used for purposes not listed in this medication guide.

Candesartan side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Candesartan may cause serious side effects. Call your doctor at once if you have:

a light-headed feeling, like you might pass out;

little or no urination; or

high potassium level--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.

Common side effects of candesartan may include:

high potassium;

headache, back pain;

cold symptoms such as stuffy or runny nose, sneezing, sore throat;

dizziness; or

abnormal kidney test.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Candesartan

You should not use this medication if you are allergic to candesartan.

If you have diabetes, do not take candesartan with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking candesartan with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

a heart condition other than one being treated with candesartan;

kidney disease (or if you are on dialysis);

liver disease; or

if you are on a low-salt diet.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Candesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

If you plan to get pregnant, ask your doctor for a safer medicine to use before and during pregnancy. Having high blood pressure during pregnancy may cause complications in the mother and the baby.

You should not breastfeed while using candesartan.

Relate drugs

How to use Candesartan

Usual Adult Dose for Hypertension:

Initial dose: 16 mg orally once a dayMaintenance dose: 8 to 32 mg/day orally in 1 to 2 divided dosesMaximum dose: 32 mg/dayComments:-Consider administration of a lower initial dose in volume depleted patients.-Most of the antihypertensive effect is present within 2 weeks; maximum blood pressure reduction at a given dose is generally observed within 4 to 6 weeks of starting that dose.

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 4 mg orally once a day; double dose every 2 weeks, as tolerated, to target dose of 32 mg orally once a dayUse: Treatment of New York Heart Association (NYHA) class II through IV heart failure

Usual Pediatric Dose for Hypertension:

1 TO LESS THAN 6 YEARS:Initial dose: 0.2 mg/kg/day orally in 1 to 2 divided dosesMaintenance dose: 0.05 to 0.4 mg/kg/day orally in 1 to 2 divided doses6 TO LESS THAN 17 YEARS:Less than 50 kg:-Initial dose: 4 to 8 mg/day orally in 1 to 2 divided doses-Maintenance dose: 2 to 16 mg/day orally in 1 to 2 divided dosesGreater than 50 kg:-Initial dose: 8 to 16 mg/day orally in 1 to 2 divided doses-Maintenance dose: 4 to 32 mg/day orally in 1 to 2 divided dosesComments:-For patients with possible intravascular volume depletion (e.g., patients treated with diuretics, especially those with renal impairment), initiate this drug under close supervision and consider administration of a lower dose.-Antihypertensive effect is present within 2 weeks; maximum blood pressure reduction at a given dose is generally observed within 4 weeks of starting that dose.-For children unable to swallow tablets, an extemporaneous suspension may be used instead.

Warnings

Do not use if you are pregnant. Stop using candesartan and tell your doctor right away if you become pregnant.

If you have diabetes, do not take candesartan with any medication that contains aliskiren (a blood pressure medicine).

What other drugs will affect Candesartan

Tell your doctor about all your other medicines, especially:

any other heart or blood pressure medications;

a diuretic or "water pill";

lithium; or

NSAIDs (nonsteroidal anti-inflammatory drugs)--ibuprofen (Advil, Motrin), naproxen (Aleve), Celecoxib, Diclofenac, Indomethacin, Meloxicam, and others.

This list is not complete. Other drugs may affect candesartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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