Carrot Oil

Generic name: Daucus Carota L. (wild Carrot), Daucus Carota L. Subspecies Sativus (Hoffm.) Archang. (common Carrot)
Brand names: Bird's Nest, Bishop's Lace, Carrot (seed, Root, Leaf), Oil Of Carrot, Pastinocello, Purple Carrot, Queen Anne's Lace, Wild Carrot

Usage of Carrot Oil

Antimicrobial effects

In vitro data

In vitro, wild carrot seed oil has demonstrated antifungal activity.Alves-Silva 2016 Activity of the seed oil and carrot root juice against common human pathogens, including EscheriChia coli, Salmonella typhimurium, and Staphylococcus aureus, has also been shown.Degirmenci 2012, Khan 2009, Rokbeni 2013 Activity of the essential oil is more evident against gram-positive organisms than gram-negative organisms.Alves-Silva 2016, Gaglio 2017

Antioxidant effects

Animal and in vitro data

An extract of D. carota has demonstrated hepatoprotective effects against carbon tetrachloride–induced intoxication in mouse liver.Bishayee 1995 Protection against renal ischemia reperfusion injury in rats has also been demonstrated with D. carota root extract.Afzal 2013 Additionally, carrot leaves reduced hepatocellular toxicity and oxidative stress in a murine model.Ebeid 2015

Clinical data

There are no clinical data regarding the use of carrot oil for antioxidant activity; however, carrot is recognized as a source of the dietary antioxidant vitamin A.

Cardiovascular effects

In vitro data

Carrot seed oil has exhibited smooth muscle relaxant, vasodilatory, and cardiosuppressant activities in isolated animal organ studies.Khan 2009

Cytotoxic effects

Animal and in vitro data

In an animal model of tongue carcinogenesis, purple carrot extract reduced oral lesions (diagnosed as dysplasia and squamous cell carcinoma) caused by 4-nitroquinoline 1-oxide.Soares 2018

In a murine model of induced skin carcinogenesis, a wild carrot oil extract demonstrated cytotoxic effects.Shebaby 2017

Dietary effects

Widespread consumption of carrot roots and leaves as part of the human diet make data from animal studies irrelevant.

Clinical data

Plasma concentrations of total carotenoids increase with consumption of carrot juiceButalla 2012; however, in the Australian QUENCH trial, no effect was demonstrated on body mass or composition, lipid profile, blood pressure, or C-reactive protein at 4 weeks following consumption of anthocyanins 118.5 mg/day and phenolic acids 259.2 mg/day from dried purple carrot.Wright 2013 A meta-analysis suggested that dietary carrot intake was associated with a reduction in the risk of breast cancer.Chen 2018

Female sexual dysfunction

Clinical data

A small clinical study in Persia demonstrated beneficial effects of D. carota, given for 8 weeks in combination with other herbals, on sexual desire, lubrication, orgasm, and pain associated with female sexual dysfunction.Molkara 2018

Nephroprotective effects

Animal data

In a murine model of gentamicin-induced nephrotoxicity, an ethanolic root extract of D. carota decreased serum urea, blood urea nitrogen, uric acid, and creatinine in a dose-dependent manner. Histopathological improvements were also noted with D. carota.Sodimbaku 2016

Osteoporosis

In vitro data

In an in vitro study, D. carota extract inhibited osteoclastic differentiation while promoting osteoblastic differentiation.Suzuki 2019

Urolithiasis

Animal data

An extract of D. carota roots demonstrated beneficial effects in a murine model of urolithiasis by exerting anticrystallization effects and improving urine and serum biochemical parameters.Bawari 2019

Carrot Oil side effects

Case reports describe carotenemia appearing as jaundice as a result of excessive carrot consumption, with one report of an increase in liver enzymes.Keown 2014, Sansone 2012 Another case report describes toxic methemoglobinemia in a 2-month-old infant given carrots. Carrots contain nitrates that are converted to nitrites, which leads to production of methemoglobin. This is problematic in infants because of their compromised hemoglobin oxidation capacity.Khemiri 2009 Allergic contact dermatitis in a man who prepared and consumed carrots was linked to the falcarinol component, based on allergen testing.Kawai 2014 Another case report describes phytophotodermatitis, which was likely due to a carrot extract–containing sunscreen and not explained by other causes.Bosanac 2018

Because myristicin, a known psychoactive agent, is a component of carrot seed, ingestion of large amounts of D. carota may cause neurological effects. Allergy and phototoxicity are also possible.Duke 2002

Before taking Carrot Oil

Avoid use. Emmenagogue and abortifacient effects of D. carota have been reported.Courraud 2013, Ernst 2002, Jansen 2014, Khan 2009, Rokbeni 2013 Antifertility effects have been demonstrated in rats.Duke 2002, Khan 2009 Excessive consumption of carrot root should be avoided during pregnancy and lactation. Beta-carotene and carrot flavoring are transmitted in breast milk; excessive maternal intake can lead to carotenemia in a breastfeeding infant.LactMed 2018

How to use Carrot Oil

Clinical trials are lacking to provide dosing recommendations.

Beta-carotene content is highest when raw carrot roots are consumed; steaming or boiling for less than 15 minutes limits loss of potency.Imsic 2010, Schnäbele 2008 Vitamin A bioavailability in carrot root juice is higher than in cooked and raw spinach.Courraud 2013

Warnings

Carrot seed oil is classified as GRAS, and carrot root oil has been approved for use as a food colorant. Antifertility effects of seed extracts have been demonstrated in rats.Khan 2009

What other drugs will affect Carrot Oil

None well documented.

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