Cefepime

Generic name: Cefepime
Drug class: Fourth generation cephalosporins

Usage of Cefepime

Cefepime injection is used to treat bacterial infections in many different parts of the body. It belongs to the class of medicines known as cephalosporin antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is to be given only by or under the direct supervision of a doctor.

Cefepime side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

Abdominal or stomach cramps

back, leg, or stomach pains

bleeding gums, nosebleeds

confusion

convulsions

dark urine

difficulty with breathing

fever, chills

general body swelling

headache

irregular heartbeats

loss of appetite

mood or mental changes

muscle cramps in the hands, arms, feet, legs, or face

nausea or vomiting

numbness and tingling around the mouth, fingertips, or feet

tremor

yellowing of the eyes or skin

Less common

Bluish color

pain, tenderness

swelling of the foot or leg

Rare

Diarrhea

inflammation or swelling

watery or bloody diarrhea

Incidence not known

Agitation

blistering, peeling, or loosening of the skin

bloody or cloudy urine

bloody, black, or tarry stools

blurred vision

change in consciousness

chest pain

cough or hoarseness

difficult or painful urination

difficulty with swallowing

dizziness

fast heartbeat

general feeling of tiredness or weakness

itching, hives

muscle twitching or jerking

paralysis

pinpoint red spots on the skin

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

red skin lesions, often with a purple center

rhythmic movement of the muscles

seeing, hearing, or feeling things that are not there

seizures

severe sleepiness

stiff neck

sudden decrease in the amount of urine

swollen or painful glands

unpleasant breath odor

unusual bleeding or bruising

vomiting of blood

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Red streaks on the skin

swelling, tenderness, or pain at the injection site

Rare

Itching of the vagina or genital area

pain during sexual intercourse

redness of the skin

sore mouth or tongue

thick, white vaginal discharge with no odor or with a mild odor

white patches in the mouth, tongue, or throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Before taking Cefepime

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of cefepime injection in children. However, safety and efficacy have not been established in children younger than 2 months of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of cefepime injection in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving cefepime injection.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Cholera Vaccine, Live

Furosemide

Warfarin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

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How to use Cefepime

A nurse or other trained health professional will give you or your child this medicine. This medicine is given as a shot into a muscle or into a vein.

Warnings

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Cefepime injection may cause diarrhea, and in some cases it can be severe. It may occur 2 months or more after you or your child stop using this medicine. Do not take any medicine or give medicine to your child to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

Tell your doctor right away if you or your child have any of the following symptoms while receiving this medicine: confusion, loss of consciousness, jerking or twitching of the muscles, seizures, seeing, hearing, or feeling things that are not there, or severe sleepiness.

Before you or your child have any medical tests, tell the medical doctor in charge that you are receiving this medicine. The results of some tests may be affected by this medicine.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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