Cetrorelix injectable

Generic name: Cetrorelix (injectable)
Brand names: Cetrotide
Dosage form: subcutaneous powder for injection (0.25 mg)
Drug class: Gonadotropin-releasing hormone antagonists

Usage of Cetrorelix injectable

Cetrorelix is a man-made form of a protein that blocks the effects of certain hormones in the body that control ovulation (release of an egg from the ovary). If ovulation occurs too soon during fertility treatment, the eggs may not be suitable for fertilization. Cetrorelix works by preventing eggs from being released too early (premature ovulation).

Cetrorelix is used to prevent premature ovulation during controlled ovarian stimulation.

Cetrorelix may also be used for purposes not listed in this medication guide.

Cetrorelix injectable side effects

Get emergency medical help if you have signs of an allergic reaction: hives or rash; cough, difficult breathing; feeling light-headed; swelling of your face, lips, tongue, or throat.

Some women using cetrorelix develop a condition called ovarian hyperstimulation syndrome (OHSS), especially after the first treatment. OHSS can be a life threatening condition.

Call your doctor right away if you have any of the following symptoms of OHSS:

stomach pain, bloating;

nausea, vomiting, diarrhea;

rapid weight gain, especially in your face and midsection;

little or no urination; or

pain when you breathe, rapid heart rate, feeling short of breath (especially when lying down).

Common side effects of cetrorelix may include:

nausea;

headache; or

redness, bruising, itching, or swelling where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Cetrorelix injectable

You should not use cetrorelix if you are allergic to it, or if:

you have severe kidney disease;

you are pregnant;

you are breast-feeding a baby;

you are allergic to mannitol; or

you have had an allergic reaction to other gonadotropin-releasing hormone medications (such as Lupron, Antagon, Zoladex, Synarel, Zoladex, or others).

Using cetrorelix if you are already pregnant can cause birth defects, miscarriage, or stillbirth. Do not use if you are pregnant. You may need to have a negative pregnancy test before starting this treatment.

It is not known whether cetrorelix passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using cetrorelix.

To make sure cetrorelix is safe for you, tell your doctor if you have:

kidney disease; or

liver disease.

Relate drugs

How to use Cetrorelix injectable

Usual Adult Dose for Ovulation Induction:

0.25 mg suBCutaneously on either stimulation day 5 (morning or evening) or day 6 (morning) and continuing daily until the day of human chorionic gonadotropin (HCG) administration Comments:-This drug is for subcutaneous injection into the lower abdominal wall.-When assessment by ultrasound shows a sufficient number of follicles of adequate size, HCG is administered to induce ovulation and final maturation of the oocytes. No HCG should be administered if the ovaries show an excessive response to the treatment with gonadotropins to reduce the chance of developing ovarian hyperstimulation syndrome (OHSS).Use: For the inhibition of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation

Warnings

You should not use cetrorelix if you have severe kidney disease, if you are pregnant or breast-feeding, or if you have ever had an allergic reaction to a medicine similar to cetrorelix (such as Lupron, Antagon, Zoladex, Synarel, Zoladex, or others).

What other drugs will affect Cetrorelix injectable

Other drugs may interact with cetrorelix, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Disclaimer

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