Chlophedianol, phenylephrine, and pyrilamine

Generic name: Chlophedianol, Phenylephrine, And Pyrilamine
Brand names: Pro-Chlo
Dosage form: oral liquid (12.5 mg-5 mg-12.5 mg/5 mL)
Drug class: Upper respiratory combinations

Usage of Chlophedianol, phenylephrine, and pyrilamine

Chlophedianol is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Pyrilamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Chlophedianol, phenylephrine, and pyrilamine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, cough, and sinus congestion caused by allergies, the common cold, or the flu.

chlophedianol, phenylephrine, and pyrilamine will not treat a cough that is caused by smoking, asthma, bronchitis, or emphysema.

Chlophedianol, phenylephrine, and pyrilamine may also be used for purposes not listed in this medication guide.

Chlophedianol, phenylephrine, and pyrilamine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

chests tightness, wheezing, shortness of breath;

severe drowsiness;

a light-headed feeling, like you might pass out;

little or no urinating;

severe dizziness or anxiety; or

severe restless feeling or being unable to sleep.

Common side effects of chlophedianol, phenylephrine, and pyrilamine may include:

mild dizziness or drowsiness;

dry mouth, nose, or throat;

diarrhea, constipation, upset stomach;

feeling restless or excited (especially in children);

blurred vision; or

sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Chlophedianol, phenylephrine, and pyrilamine

Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not use this medicine if you are allergic to chlophedianol, phenylephrine, or pyrilamine.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:

any type of breathing disorder;

blockage in your intestines;

bladder obstruction or other urination problems;

cough with mucus;

glaucoma;

diabetes;

liver or kidney disease;

heart disease, high blood pressure;

a thyroid disorder; or

if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

FDA pregnancy category C. It is not known whether chlophedianol, phenylephrine, and pyrilamine will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Chlophedianol, phenylephrine, and pyrilamine may pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Relate drugs

How to use Chlophedianol, phenylephrine, and pyrilamine

Usual Adult Dose for Cough and Nasal Congestion:

Chlophedianol/phenylephrine/pyrilamine 12.5 mg-5 mg-12.5 mg/5 mL oral liquid:10 mL orally every 6 hours not to exceed 40 mL/daily.

Usual Pediatric Dose for Cough and Nasal Congestion:

Chlophedianol/phenylephrine/pyrilamine 12.5 mg-5 mg-12.5 mg/5 mL oral liquid:6 to 11 years: 5 mL orally every 6 hours not to exceed 20 mL/daily12 years or older:10 mL orally every 6 hours not to exceed 40 mL/daily.

Warnings

Do not use chlophedianol, phenylephrine, and pyrilamine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

What other drugs will affect Chlophedianol, phenylephrine, and pyrilamine

Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.

Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking chlophedianol, phenylephrine, and pyrilamine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

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