Chlorcyclizine and pseudoephedrine

Generic name: Chlorcyclizine And Pseudoephedrine
Dosage form: oral tablet (25 mg-60 mg)
Drug class: Upper respiratory combinations

Usage of Chlorcyclizine and pseudoephedrine

Chlorcyclizine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Chlorcyclizine and pseudoephedrine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, sinus congestion, and other cold or allergy symptoms.

Chlorcyclizine and pseudoephedrine may also be used for purposes not listed in this medication guide.

Chlorcyclizine and pseudoephedrine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

chlorcyclizine and pseudoephedrine may cause serious side effects. Stop using chlorcyclizine and pseudoephedrine and call your doctor at once if you have:

  • fast or uneven heart rate;
  • tremor, seizure (convulsions);
  • urinating less than usual or not at all; or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, uneven heartbeats, seizure).
  • Common side effects of chlorcyclizine and pseudoephedrine may include:

  • dizziness, drowsiness;
  • constipation;
  • blurred vision; or
  • feeling nervous or restless.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Chlorcyclizine and pseudoephedrine

    You should not use chlorcyclizine and pseudoephedrine if you are allergic to chlorcyclizine or pseudoephedrine.

    Do not use chlorcyclizine and pseudoephedrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

    Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:

  • high blood pressure;
  • coronary artery disease (hardened arteries),
  • bladder obstruction or other urination problems; or
  • if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).
  • It is not known whether this medication will harm an unborn baby. Do not use cough or cold medicine without medical advice if you are pregnant.

    This medicine may pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use cough or cold medicine without medical advice if you are breast-feeding a baby.

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    How to use Chlorcyclizine and pseudoephedrine

    Usual Adult Dose for Nasal Congestion:

    Chlorcyclizine-pseudoephedrine 25 mg-60 mg oral tablet:1 tablet orally every 6 to 8 hours not to exceed 3 tablets daily.Chlorcyclizine-pseudoephedrine 9.375 mg-30 mg/5 mL oral liquid:10 mL orally every 6 hours not to exceed 40 mL daily.

    Usual Pediatric Dose for Nasal Congestion:

    Chlorcyclizine-pseudoephedrine 25 mg-60 mg oral tablet:6 to 11 years: 1/2 tablet orally every 6 to 8 hours not to exceed 1 1/2 tablets daily.12 years or older: 1 tablet orally every 6 to 8 hours not to exceed 3 tablets daily.Chlorcyclizine-pseudoephedrine 9.375 mg-30 mg/5 mL oral liquid:6 to 11 years: 5 mL orally every 6 hours not to exceed 20 mL daily.12 years or older: 10 mL orally every 6 hours not to exceed 40 mL daily.

    Warnings

    Do not use chlorcyclizine and pseudoephedrine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

    What other drugs will affect Chlorcyclizine and pseudoephedrine

    Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.

    Taking this medicine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking chlorcyclizine and pseudoephedrine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

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