Chlorothiazide (Intravenous)

Generic name: Chlorothiazide
Drug class: Thiazide diuretics

Usage of Chlorothiazide (Intravenous)

Chlorothiazide is used to treat fluid retention (edema) that is caused by congestive heart failure, severe liver disease (cirrhosis), kidney disease, or from treatment with a steroid or hormone medicine.

Chlorothiazide is a thiazide diuretic. It reduces the amount of water in the body by increasing the flow of urine, which helps reduce fluid retention (edema).

This medicine is available only with your doctor's prescription.

Chlorothiazide (Intravenous) side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

Abdominal or stomach pain

back, leg, or stomach pains

black, tarry stools

bleeding gums

blisters on skin

blood in urine or stools

bloody or cloudy urine

blue lips and fingernails

blurred vision

burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

chest pain

chills

clay-colored stools

cold sweats

confusion

constipation

cough or hoarseness

coughing that sometimes produces a pink frothy sputum

coughing up blood

darkened urine

decrease in urine output or decrease in urine-concentrating ability

decreased frequency or amount of urine

diarrhea

difficult, fast, or noisy breathing, sometimes with wheezing

difficulty swallowing

dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

dry mouth

fast heartbeat

feeling of constant movement of self or surroundings

fever

flushed, dry skin

fruit-like breath odor

general feeling of discomfort or illness

general feeling of tiredness or weakness

headache

hives

increased blood pressure

increased hunger

increased sensitivity of skin to sunlight

increased sweating

increased thirst

increased urination

indigestion

itching

joint pain, stiffness, or swelling

loss of appetite

lower back or side pain

muscle cramps or pain

nausea

nosebleeds

numbness, tingling, pain, or weakness in hands or feet

pain in joints or muscles

painful or difficult urination

pains in stomach, side, or abdomen, possibly radiating to the back

pale skin

pinpoint red spots on skin

puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

redness or other discoloration of skin

redness, soreness, or itching skin

seizures

sensation of spinning

severe sunburn

shortness of breath

skin rash

sores, ulcers, or white spots on lips or in mouth

sores, welting, or blisters

sugar in the urine

sweating

swelling in legs and ankles

swelling of face, fingers, or lower legs

swollen or painful glands

tenderness of salivary glands

thickening of bronchial secretions

tightness in chest

trembling

troubled breathing

unexplained weight loss

unpleasant breath odor

unusual bleeding or bruising

unusual tiredness or weakness

unusual weight loss

vomiting of blood

weight gain

yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Blistering, peeling, or loosening of skin

cracks in the skin

cramping

decreased interest in sexual intercourse

difficulty having a bowel movement (stool)

hair loss, thinning of hair

inability to have or keep an erection

loss in sexual ability, desire, drive, or performance

loss of heat from the body

muscle spasm

pinpoint red or purple spots on skin

red, irritated eyes

red, swollen skin

restlessness

scaly skin

weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Before taking Chlorothiazide (Intravenous)

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of chlorothiazide in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of chlorothiazide in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require an adjustment in the dose for patients receiving chlorothiazide.

Breast Feeding

Studies suggest that this medication may alter milk production or composition. If an alternative to this medication is not prescribed, you should monitor the infant for side effects and adequate milk intake.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acarbose

Aceclofenac

Acemetacin

Acetyldigoxin

Albiglutide

Albuterol

Alogliptin

Amphetamine

Amtolmetin Guacil

Arsenic Trioxide

Aspirin

Bepridil

Bufexamac

Celecoxib

Chlorpropamide

Choline Salicylate

Clonixin

Codeine

Dapagliflozin

Deslanoside

Desmopressin

Dexibuprofen

Dexketoprofen

Dextroamphetamine

Diclofenac

Diflunisal

Digitalis

Digitoxin

Digoxin

Dipyrone

Dofetilide

Droxicam

Dulaglutide

Empagliflozin

Etodolac

Etofenamate

Etoricoxib

Exenatide

Felbinac

Fenoprofen

Fepradinol

Feprazone

Flecainide

Floctafenine

Flufenamic Acid

Flurbiprofen

Formoterol

Glimepiride

Glipizide

Glyburide

Ibuprofen

Indomethacin

Insulin

Insulin Aspart, Recombinant

Insulin Bovine

Insulin Degludec

Insulin Detemir

Insulin Glulisine

Ketanserin

Ketoprofen

Ketorolac

Linagliptin

Liraglutide

Lisdexamfetamine

Lithium

Lixisenatide

Lornoxicam

Loxoprofen

Lumiracoxib

Meclofenamate

Mefenamic Acid

Meloxicam

Methamphetamine

Metildigoxin

Miglitol

Morniflumate

Nabumetone

Naproxen

Nateglinide

Nepafenac

Niflumic Acid

Nimesulide

Nimesulide Beta Cyclodextrin

Oxaprozin

Oxyphenbutazone

Parecoxib

Phenylbutazone

Piketoprofen

Pioglitazone

Piroxicam

Porfimer

Pramlintide

Proglumetacin

Propyphenazone

Proquazone

Repaglinide

Rofecoxib

Rosiglitazone

Salicylic Acid

Salsalate

Saxagliptin

Sitagliptin

Sodium Salicylate

Sulindac

Tapentadol

Tenoxicam

Tiaprofenic Acid

Tolazamide

Tolbutamide

Tolfenamic Acid

Tolmetin

Valdecoxib

Vildagliptin

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Aminolevulinic Acid

Calcium

Ginkgo

Gossypol

Licorice

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

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How to use Chlorothiazide (Intravenous)

A nurse or other trained health professional will give you this medicine. This medicine is given through a needle placed in one of your veins.

Warnings

Your doctor will only give you a few doses of this medicine until your condition improves, and then you will be switched to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor.

Disclaimer

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