Chlorpheniramine and hydrocodone

Generic name: Chlorpheniramine And Hydrocodone
Dosage form: oral suspension, extended release (8 mg-10 mg/5 mL)
Drug class: Upper respiratory combinations

Usage of Chlorpheniramine and hydrocodone

Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Hydrocodone is a narcotic cough suppressant. It affects the signals in the brain that trigger cough reflex.

Chlorpheniramine and hydrocodone is a combination medicine used to treat runny nose, sneezing, itching, watery eyes, and cough caused by allergies, the common cold, or the flu.

Chlorpheniramine and hydrocodone may also be used for purposes not listed in this medication guide.

Chlorpheniramine and hydrocodone side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Like other narcotic medications, hydrocodone can slow your breathing. Death may occur if breathing becomes too weak.

A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

chlorpheniramine and hydrocodone may cause serious side effects. Stop using chlorpheniramine and hydrocodone and call your doctor at once if you have:

  • severe drowsiness;
  • noisy breathing, sighing, shallow breathing;
  • severe constipation;
  • a light-headed feeling, like you might pass out;
  • a slow heart rate or weak pulse;
  • confusion; or
  • adrenal gland problems--nausea, vomiting, loss of appetite, dizziness, feeling weak or tired.
  • Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

    Common side effects of chlorpheniramine and hydrocodone may include:

  • trouble breathing;
  • drowsiness;
  • confusion;
  • nausea, vomiting; or
  • little or no urination.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Chlorpheniramine and hydrocodone

    You should not use chlorpheniramine and hydrocodone if you are allergic to chlorpheniramine or hydrocodone.

    Do not use chlorpheniramine and hydrocodone if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

    Do not give this medicine to a child younger than 6 years old. Chlorpheniramine and hydrocodone is not approved for use by anyone younger than 18 years old.

    Tell your doctor if you have ever had:

  • asthma or other breathing problems;
  • seizures, or a head injury or brain tumor;
  • a blockage in your digestive tract (stomach or intestines);
  • enlarged prostate, urination problems;
  • low blood pressure;
  • liver or kidney disease;
  • Addison's disease (an adrenal gland disorder);
  • problems with your thyroid, gallbladder, or pancreas; or
  • alcoholism or drug addiction.
  • If you use hydrocodone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

    You should not breast-feed while using chlorpheniramine and hydrocodone.

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    How to use Chlorpheniramine and hydrocodone

    Usual Adult Dose for Cold Symptoms:

    Immediate-release (IR): 5 mL orally every 4 to 6 hours as neededMaximum dose: 20 mL in 24 hours-Each 5 mL of IR oral solution contains hydrocodone bitartrate 5 mg with chlorpheniramine maleate 4 mgExtended-release (ER): One dose orally every 12 hoursMaximum dose: 2 doses in 24 hours -A dose equals 1 ER capsule or 5 mL ER suspension; each dose provides hydrocodone polistirex equivalent to 10 mg of hydrocodone bitartrate and chlorpheniramine polistirex equivalent to 8 mg chlorpheniramine maleate Comments:-Oral solution and suspension must be measured with an accurate milliliter measuring device; do not use a household teaspoon. Use: For the symptomatic relief of cough and upper respiratory symptoms associated with allergy or a cold.

    Usual Adult Dose for Cough:

    Immediate-release (IR): 5 mL orally every 4 to 6 hours as neededMaximum dose: 20 mL in 24 hours-Each 5 mL of IR oral solution contains hydrocodone bitartrate 5 mg with chlorpheniramine maleate 4 mgExtended-release (ER): One dose orally every 12 hoursMaximum dose: 2 doses in 24 hours -A dose equals 1 ER capsule or 5 mL ER suspension; each dose provides hydrocodone polistirex equivalent to 10 mg of hydrocodone bitartrate and chlorpheniramine polistirex equivalent to 8 mg chlorpheniramine maleate Comments:-Oral solution and suspension must be measured with an accurate milliliter measuring device; do not use a household teaspoon. Use: For the symptomatic relief of cough and upper respiratory symptoms associated with allergy or a cold.

    Warnings

    MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.

    Do not give this medicine to a child younger than 6 years old.

    Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.

    What other drugs will affect Chlorpheniramine and hydrocodone

    Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

    Using this medicine with other drugs that slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

    Tell your doctor about all your other medicines, especially:

  • an antibiotic or antifungal medicine;
  • antiviral medicine to treat hepatitis or HIV;
  • asthma medication;
  • bladder or urinary medicines;
  • blood pressure medication;
  • a diuretic or "water pill";
  • medicine to treat a stomach ulcer, motion sickness, or irritable bowel syndrome;
  • medicine to treat Parkinson's disease; or
  • seizure medicine.
  • This list is not complete and many other drugs may affect chlorpheniramine and hydrocodone. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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