Chlorpheniramine, phenylephrine, and pyrilamine

Generic name: Chlorpheniramine, Phenylephrine, And Pyrilamine
Drug class: Upper respiratory combinations

Usage of Chlorpheniramine, phenylephrine, and pyrilamine

Chlorpheniramine, phenylephrine, and pyrilamine is a combination medicine used to relieve the symptoms of coughs, colds, and allergies.

Chlorpheniramine, phenylephrine, and pyrilamine may also be used for purposes not listed in this medication guide.

Chlorpheniramine, phenylephrine, and pyrilamine side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Stop using chlorpheniramine, phenylephrine, and pyrilamine and call your doctor at once if you have:

  • confusion, hallucinations;
  • feeling nervous or irritable;
  • trouble sleeping;
  • little or no urination;
  • a seizure (convulsions);
  • numbness or tingly feeling;
  • a light-headed feeling, like you might pass out;
  • pounding heartbeats or fluttering in your chest; or
  • severe headache, blurred vision, pounding in your neck or ears.
  • Serious side effects may be more likely in older adults.

    Common side effects of chlorpheniramine, phenylephrine, and pyrilamine may include:

  • nausea, constipation, loss of appetite;
  • rash or itching;
  • increased sweating;
  • dry mouth, nose, or throat;
  • blurred vision;
  • headache, dizziness; or
  • feeling restless or excited (especially in children).
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Chlorpheniramine, phenylephrine, and pyrilamine

    Do not use chlorpheniramine, phenylephrine, and pyrilamine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine. Wait at least 14 days after stopping an MAO inhibitor before you take chlorpheniramine, phenylephrine, and pyrilamine.

    You should not use this medicine if you are allergic to chlorpheniramine, phenylephrine, pyrilamine, or to other decongestants, or if you have:

  • severe coronary artery disease;
  • diabetes;
  • overactive thyroid; or
  • asthma, pneumonia, or other breathing problems.
  • Tell your doctor if you have ever had:

  • heart disease or high blood pressure;
  • blood circulation problems;
  • glaucoma;
  • an ulcer or obstruction in the stomach;
  • enlarged prostate;
  • bladder obstruction or other urination problems; or
  • a history of seizures.
  • Tell your doctor if you are pregnant or breastfeeding.

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    How to use Chlorpheniramine, phenylephrine, and pyrilamine

    Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use.

    Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

    Do not give this medication to a child younger than 6 years old. Always ask a doctor before giving a cough or cold medicine to a child.

    Follow all directions when giving chlorpheniramine, phenylephrine, and pyrilamine to a child. Do not use the medicine to make a child sleepy. Misuse of this medicine may cause death in very young children.

    Shake the oral suspension (liquid). Measure a dose with the supplied measuring device (not a kitchen spoon).

    Store at room temperature away from moisture, heat, and light.

    Warnings

    You should not use chlorpheniramine, phenylephrine, and pyrilamine if you have severe coronary artery disease, diabetes, overactive thyroid, asthma, pneumonia, or other breathing problems.

    Do not use chlorpheniramine, phenylephrine, and pyrilamine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

    Do not give this medicine to a child younger than 6 years old. Misuse of this medicine may cause death in very young children.

    Do not use this medicine to make a child sleepy.

    What other drugs will affect Chlorpheniramine, phenylephrine, and pyrilamine

    Using chlorpheniramine, phenylephrine, and pyrilamine with other drugs that make you drowsy or that slow your breathing can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

    Other drugs may affect chlorpheniramine, phenylephrine, and pyrilamine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

    Disclaimer

    Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

    The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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