Cholic acid
Generic name: Cholic Acid
Brand names: Cholbam
Dosage form: oral capsule (250 mg; 50 mg)
Drug class:
Digestive enzymes
Usage of Cholic acid
Cholic acid is a bile acid. Bile acids are produced naturally in the body to aid in digestion of fats and certain nutrients.
People with bile acid disorders are unable to produce cholic acid normally. This can make it harder for the body to absorb nutrients important for health, growth, and body functioning. Abnormal bile acids can also build up in the body and become toxic to the liver.
Cholic acid is used in people with bile acid disorders. cholic acid works by normalizing bile acid production in the body.
Cholic acid may also be used for purposes not listed in this medication guide.
Cholic acid side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Cholic acid may cause serious side effects. Call your doctor at once if you have:
Common side effects of cholic acid may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Cholic acid
Tell your doctor if you have ever had:
Tell your doctor if you are pregnant or breastfeeding.
If you are pregnant, your name may be listed on a pregnancy registry to track the effects of cholic acid on the baby.
Do not give cholic acid to a child without medical advice. Cholic acid is not approved for use by anyone younger than 3 weeks old.
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How to use Cholic acid
Usual Adult Dose for Bile Acid Synthesis Disorders:
Initial dose: 10 to 15 mg/kg orally once a day or in 2 divided dosesPatients with Concomitant Familial Hypertriglyceridemia: Initial dose: 11 to 17 mg/kg orally once a day or in 2 divided dosesMaintenance dose: The lowest dose that effectively maintains liver functionComments: -Adequacy of dosing should be determined by patient monitoring of clinical response and laboratory values; monitor more frequently during periods of rapid growth, concomitant disease, and pregnancy-Concurrent elevations of serum gamma glutamyltransferase (GGT) and ALT may indicate cholic acid overdose.Uses: -For the treatment of bile acid synthesis disorders due to single enzyme defects-As adjunctive treatment of peroxisomal disorders including Zellweger spectrum disorders in patients who exhibit manifestations of liver disease, steatorrhea, or complications from decreased fat soluble vitamin absorption.
Usual Pediatric Dose for Bile Acid Synthesis Disorders:
Initial dose: 10 to 15 mg/kg orally once a day or in 2 divided dosesPatients with Concomitant Familial Hypertriglyceridemia: Initial dose: 11 to 17 mg/kg orally once a day or in 2 divided dosesMaintenance dose: The lowest dose that effectively maintains liver functionComments: -Adequacy of dosing should be determined by patient monitoring of clinical response and laboratory values; monitor more frequently during periods of rapid growth, concomitant disease, and pregnancy-Concurrent elevations of serum gamma glutamyltransferase (GGT) and ALT may indicate cholic acid overdose.Uses: -For the treatment of bile acid synthesis disorders due to single enzyme defects-As adjunctive treatment of peroxisomal disorders including Zellweger spectrum disorders in patients who exhibit manifestations of liver disease, steatorrhea, or complications from decreased fat soluble vitamin absorption.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What other drugs will affect Cholic acid
Other drugs may affect cholic acid, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
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