Clarinex-D 24 Hour

Generic name: Desloratadine And Pseudoephedrine
Drug class: Upper respiratory combinations

Usage of Clarinex-D 24 Hour

Clarinex-D 24 Hour contains a combination of desloratadine and pseudoephedrine. Desloratadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Clarinex-D 24 Hour is used to treat sneezing, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Clarinex-D 24 Hour is for adults and children who are at least 12 years old.

Clarinex-D 24 Hour side effects

Get emergency medical help if you have signs of an allergic reaction to Clarinex-D 24 Hour: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Clarinex-D 24 Hour and call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • tremors;
  • severe weakness;
  • irregular heartbeats;
  • a seizure; or
  • a severe skin reaction - fever, skin redness, small pimples.
  • Common Clarinex-D 24 Hour side effects may include:

  • drowsiness, dizziness;
  • headache
  • nausea, loss of appetite;
  • sleep problems (insomnia); or
  • dry mouth, sore throat.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Clarinex-D 24 Hour

    You should not use Clarinex-D 24 Hour if you are allergic to desloratadine, loratadine (Claritin), or pseudoephedrine, or if you have:

  • narrow-angle glaucoma;
  • severe coronary artery disease (clogged arteries);
  • uncontrolled high blood pressure; or
  • bladder obstruction or other urination problems.
  • Do not use Clarinex-D 24 Hour if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

    Tell your doctor if you have ever had:

  • kidney disease;
  • glaucoma;
  • heart disease or high blood pressure;
  • a seizure (in you or a family member);
  • diabetes;
  • thyroid disorder; or
  • an enlarged prostate.
  • Clarinex-D 24 Hour should not be given to a child younger than 12 years old.

    It is not known whether desloratadine and pseudoephedrine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

    You should not breast feed while using Clarinex-D 24 Hour.

    Relate drugs

    How to use Clarinex-D 24 Hour

    Usual Adult Dose for Allergic Rhinitis:

    desloratadine-pseudoephedrine 5 mg-240 mg oral tablet, extended release: one extended release tablet orally once daily

    Usual Pediatric Dose for Allergic Rhinitis:

    desloratadine-pseudoephedrine 5 mg-240 mg oral tablet, extended release: one extended release tablet orally once daily

    Warnings

    Do not use Clarinex-D 24 Hour if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

    What other drugs will affect Clarinex-D 24 Hour

    Using Clarinex-D 24 Hour with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety, depression, or seizures.

    Ask a doctor or pharmacist before using desloratadine and pseudoephedrine with any other medications, especially:

  • any other cold or allergy medicine;
  • ketoconazole;
  • reserpine;
  • an antibiotic - azithromycin (Zithromax, Z-Pak), erythromycin; or
  • heart or blood pressure medication - digoxin, digitalis, methyldopa.
  • This list is not complete. Other drugs may interact with desloratadine and pseudoephedrine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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