Clindamycin and tretinoin topical

Generic name: Clindamycin And Tretinoin (topical)
Dosage form: topical gel (1.2%-0.025%)
Drug class: Topical acne agents

Usage of Clindamycin and tretinoin topical

Clindamycin is an antibiotic. It fights bacteria in the body.

Tretinoin is a form of vitamin A. It reduces the amount of oil released by oil glands in your skin, and helps your skin renew itself more quickly.

Clindamycin and tretinoin is a combination medicine used to treat severe nodular acne in adults and children who are at least 12 years old.

Clindamycin and tretinoin topical may also be used for purposes other than those listed in this medication guide.

Clindamycin and tretinoin topical side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

clindamycin and tretinoin may cause serious side effects. Stop using clindamycin and tretinoin and call your doctor at once if you have:

  • severe redness, burning, stinging, or scaling of treated skin areas; or
  • diarrhea that is watery or bloody.

    • Common side effects of clindamycin and tretinoin may include:

  • mild skin irritation, dryness or peeling;
  • mild skin redness; or
  • itching of treated skin.

    • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Clindamycin and tretinoin topical

    Although clindamycin and tretinoin is applied to the skin, your body may absorb enough clindamycin to affect certain medical conditions you may have.

    You should not use this medication if you are allergic to clindamycin or tretinoin, or if you have:

  • inflammation of your intestines (also called enteritis);
  • Crohn's disease, ulcerative colitis; or
  • if you have ever had severe diarrhea caused by antibiotic medicine.

    • You should not use clindamycin and tretinoin topical if you are also taking another antibiotic called erythromycin, or using other skin medications that contain erythromycin.

    To make sure clindamycin and tretinoin topical is safe for you, tell your doctor if you have:

  • any allergies; or
  • a history of stomach or intestinal disorders.

    • FDA pregnancy category C. It is not known whether clindamycin and tretinoin topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

    It is not known whether clindamycin and tretinoin topical passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

    This medicine should not be used on a child younger than 12 years old.

    Relate drugs

    How to use Clindamycin and tretinoin topical

    Usual Adult Dose for Acne:

    At bedtime, squeeze a pea-sized amount of medication into one fingertip, dot it onto the chin, cheeks, nose, and forehead, and then gently rub over the entire face.Comments: Avoid the eyes, lips, and mucous membranes. This medication is not for oral, ophthalmic, intranasal or intravaginal use.Use: Topical treatment of acne vulgaris in patients 12 years or older.

    Usual Pediatric Dose for Acne:

    Patients 12 years through 18 years: At bedtime, squeeze a pea-sized amount of medication into one fingertip, dot it onto the chin, cheeks, nose, and forehead, and then gently rub over the entire face.Comments: Avoid the eyes, lips, and mucous membranes. This medication is not for oral, ophthalmic, intranasal or intravaginal use.Use: Topical treatment of acne vulgaris in patients 12 years or older.

    Warnings

    You should not use this medication if you have ulcerative colitis, Crohn's disease, inflammation of your intestines (also called enteritis), or if you have ever had severe diarrhea caused by antibiotic medicine.

    You should not use clindamycin and tretinoin topical if you are also taking another antibiotic called erythromycin, or using other skin medications that contain erythromycin.

    What other drugs will affect Clindamycin and tretinoin topical

    It is not likely that other drugs you take orally or inject will have an effect on topically applied clindamycin and tretinoin. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

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