Codeine, phenylephrine, and triprolidine

Generic name: Codeine, Phenylephrine, And Triprolidine
Brand names: Histex-AC
Dosage form: oral liquid (10 mg-10 mg-2.5 mg/5 mL)
Drug class: Upper respiratory combinations

Usage of Codeine, phenylephrine, and triprolidine

Triprolidine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Codeine is a narcotic cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Codeine, phenylephrine, and triprolidine is a combination medicine used to treat runny or stuffy nose, sneezing, itching, watery eyes, cough, and sinus congestion caused by allergies, the common cold, or the flu.

codeine, phenylephrine, and triprolidine will not treat a cough that is caused by smoking, asthma, or emphysema.

Codeine, phenylephrine, and triprolidine may also be used for purposes not listed in this medication guide.

Codeine, phenylephrine, and triprolidine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Like other narcotic medications, codeine can slow your breathing. Death may occur if breathing becomes too weak.

A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Like other narcotic medications, codeine can slow your breathing. Death may occur if breathing becomes too weak.

Stop taking this medicine and call your doctor at once if you have:

noisy breathing, sighing, shallow breathing;

a slow heart rate or weak pulse;

nervousness, trouble sleeping;

severe headache or dizziness, ringing in your ears;

severe constipation; or

little or no urination.

Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.

Common side effects of codeine, phenylephrine, and triprolidine may include:

dizziness, drowsiness, tired feeling;

dry mouth, nose, or throat;

blurred vision;

nausea, vomiting, constipation; or

sleep problems (insomnia).

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Codeine, phenylephrine, and triprolidine

You should not use this medicine if you are allergic to codeine, phenylephrine, or triprolidine.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

In some people, codeine breaks down rapidly in the liver and reaches higher than normal levels in the body. This can cause dangerously slow breathing and may cause death, especially in a child.

Do not give this medicine to anyone younger than 18 years old.

To make sure this medicine is safe for you, tell your doctor if you have:

asthma, COPD, bronchitis, or other breathing disorders;

a cough with mucus;

heart disease, high blood pressure;

glaucoma;

diabetes;

a thyroid disorder; or

enlarged prostate and urination problems.

If you use codeine while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

Do not breast-feed. Codeine can pass into breast milk and may cause drowsiness, breathing problems, or death in a nursing baby. Triprolidine may slow breast milk production.

Relate drugs

How to use Codeine, phenylephrine, and triprolidine

Usual Adult Dose for Cough and Nasal Congestion:

5 mL orally every 4 hours Maximum dose: 20 mL in 24 hours Comments: -Each 5 mL contains codeine 10 mg-phenylephrine 10 mg-triprolidine 2.5 mg -Liquid preparations should be measured with an accurate milliliter measuring device.Uses: Temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold.

Warnings

Codeine can slow or stop your breathing, and may be habit-forming. MISUSE OF codeine, phenylephrine, and triprolidine CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.

This medicine is not for use in anyone under 18.

You should not use antihistamine medication to make a child sleepy.

What other drugs will affect Codeine, phenylephrine, and triprolidine

Ask a doctor or pharmacist before using this medicine if you are also using any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.

Taking codeine, phenylephrine, and triprolidine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.

Disclaimer

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