Copegus

Generic name: Ribavirin (oral)

Usage of Copegus

Copegus is an antiviral medication that is used to treat chronic hepatitis C.

Copegus is not effective when used alone. Copegus must be used in combination with interferon alfa or peginterferon alfa.

Copegus is sometimes given to people taking other antiviral medications to treat hepatitis C.

Copegus may also be used for purposes not listed in this medication guide.

Copegus side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Copegus can cause anemia. In rare cases, this can lead to fatal heart problems. Get emergency medical attention if you have chest pain.

Copegus may cause serious side effects. Call your doctor at once if you have:

problems with your vision;

severe pain in your upper stomach spreading to your back, nausea, vomiting, diarrhea;

new or worsening cough, fever, stabbing chest pain, wheezing, feeling short of breath;

severe depression, thoughts about suicide, or thoughts about hurting someone else;

signs of serious anemia--pale or yellowed skin, dark colored urine, confusion or weakness; or

other signs of low blood cell counts--fever, chills, flu-like symptoms, swollen gums, mouth sores, skin sores, easy bruising, unusual bleeding, feeling light-headed.

Copegus can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common side effects of Copegus may include:

nausea, vomiting, loss of appetite;

fever, chills or shaking;

low blood cell counts, anemia;

feeling weak or tired;

headache, muscle pain; or

mood changes, feeling anxious or irritable.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Copegus

You should not take Copegus if you are allergic to it, or if you have:

a hemoglobin blood cell disorder such as sickle-cell anemia or thalassemia;

autoimmune hepatitis;

moderate to severe kidney disease;

if you are also taking didanosine; or

if you are pregnant, or if you are a man whose sex partner is pregnant.

When you take Copegus in combination with other medications: There may be other reasons you should not take the combination treatment. Tell your doctor about all your medical conditions.

Tell your doctor if you have ever had:

a blood cell disorder such as anemia (low red blood cells);

heart problems, high blood pressure, or heart attack;

breathing problems;

vision problems (you may need an eye exam before taking Copegus);

diabetes;

human immunodeficiency virus (HIV or AIDS) or a weak immune system;

depression, mental illness, thoughts of hurting yourself or others;

a thyroid disorder;

kidney disease;

an organ transplant;

liver problems other than hepatitis C; or

treatment for hepatitis C that did not work well.

Both men and women taking Copegus should use effective birth control to prevent pregnancy. This medicine can cause birth defects, miscarriage, or death to an unborn baby if the mother or father is using this medicine.

If you are a woman, do not take Copegus if you are pregnant. You will need to have a negative pregnancy test before taking this medicine. You will also need pregnancy tests during treatment and for 6 months after your last dose.

If you are a man, do not take Copegus if your sex partner is pregnant.

Both men and women should keep using effective birth control for at least 6 months after the last dose of Copegus.

Tell your doctor right away if a pregnancy occurs while either the mother or the father is taking Copegus. Your name may be listed on a pregnancy registry to track the effects of Copegus on the baby.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Copegus is not approved for use by anyone younger than 3 years old. This medicine tablets are not approved for use by anyone younger than 5 years old.

How to use Copegus

Copegus is not effective when used alone and must be used in combination with other medications to treat hepatitis C.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take Copegus with food.

Swallow the capsule whole and do not crush, chew, break, or open it. Tell your doctor if you have trouble swallowing the capsule.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Drink extra fluids while you are taking Copegus to keep from getting dehydrated.

Copegus can cause dry mouth, which could lead to tooth decay or gum disease. If you vomit while taking this medicine, rinse your mouth out with water to prevent damage to your teeth or gums. Be sure to have regular dental exams while you are taking this medication.

You will need frequent medical tests.

Store Copegus tablets or capsules at room temperature away from moisture, heat, and light.

Store Copegus liquid (oral solution) at room temperature or in the refrigerator.

Warnings

You should not use Copegus if you have autoimmune hepatitis, moderate to severe kidney disease, a hemoglobin blood cell disorder, or if you take didanosine.

Copegus can harm an unborn baby if the mother or the father is using Copegus. Do not use if you are pregnant, or if you are a man whose sex partner is pregnant. Both men and women should use effective birth control while taking this medicine and for at least 6 months after the last dose.

Copegus is not effective when used alone and must be used in combination with an interferon.

In rare cases, Copegus can cause fatal heart problems. Get emergency medical attention if you have chest pain.

What other drugs will affect Copegus

Tell your doctor about all your other medicines, especially:

azathioprine; or

medicines to treat HIV or AIDS.

This list is not complete. Other drugs may affect Copegus, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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