Corkwood Tree

Generic name: Duboisia Hopwoodii, Duboisia Leichhardtii, Duboisia Myoporoides R. Br.
Brand names: Corkwood Tree, Pituri

Usage of Corkwood Tree

There are no recent clinical studies of corkwood to provide a basis for therapeutic recommendations. Corkwood is used as a source of purified alkaloids, particularly scopolamine, in the pharmaceutical industry.Ullrich 2017 Older reports suggest corkwood leaves have been used as an antidote to the GI symptoms of ciguatera poisoning from consumption of toxin-contaminated reef fish.Dufva 1976

Corkwood Tree side effects

Corkwood has demonstrated stimulant and hallucinogenic properties due to the anticholinergic effects of its major alkaloid constituents (eg, hyoscine).Duke 2003, Pearn 1981 A case report describes a 22-year-old man who presented to the emergency department with agitated delirium and visual hallucinations following ingestion of 5 to 10 leaves from the D. myoporoides plant.Pellowe 2013

Before taking Corkwood Tree

Avoid use. Information regarding safety and efficacy in pregnancy and lactation is lacking.

How to use Corkwood Tree

There are no recent clinical studies of corkwood to provide a basis for dosing recommendations. Corkwood should be used with caution because of its high anticholinergic alkaloid content.

Warnings

Ingestion of scopolamine and related alkaloids of D. myoporoides can be fatal in large doses due to competitive inhibition of central and peripheral acetylcholine muscarinic receptors.Pellowe 2013

What other drugs will affect Corkwood Tree

None well documented.

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