Cosela

Generic name: Trilaciclib
Drug class: Other immunostimulants

Usage of Cosela

Cosela is used to help prevent bone marrow suppression in people receiving chemotherapy with certain medicines to treat small cell lung cancer.

Cosela may also be used for purposes not listed in this medication guide.

Cosela side effects

Get emergency medical help if you have signs of an allergic reaction: hives, itching; difficult breathing; swelling of your eyes, face, lips, tongue, or throat.

Cosela may cause serious side effects. Call your doctor at once if you have:

pain, redness, warmth, itching, swelling, bruising, or skin changes where the medicine was injected;

fever, chills, cough with mucus;

sudden chest pain, wheezing, dry cough, feeling short of breath;

low calcium level--muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes); or

low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.

Your Cosela treatments may be delayed or permanently discontinued if you have certain side effects.

Common side effects of Cosela may include:

low levels of calcium or potassium;

headache;

breathing problems;

feeling tired; or

abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Cosela

You should not be treated with Cosela if you are allergic to it.

Tell your doctor if you have ever had liver problems.

Cosela may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using Cosela and for at least 3 weeks after your last dose. Tell your doctor if you become pregnant.

You should not breastfeed while using Cosela and for at least 3 weeks after your last dose.

Relate drugs

How to use Cosela

Cosela is given as an infusion into a vein, usually within 4 hours before the start of your chemotherapy infusion. A healthcare provider will give you this injection.

Cosela must be given slowly, and the infusion can take at least 30 minutes to complete.

Warnings

Call your doctor at once if you have pain, redness, warmth, itching, swelling, bruising, or skin changes where the medicine was injected.

What other drugs will affect Cosela

Tell your doctor about all your other medicines, especially:

cisplatin;

dalfampridine; or

dofetilide.

This list is not complete. Other drugs may affect Cosela, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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