Cyanocobalamin injection

Generic name: Cyanocobalamin (injection)
Dosage form: injectable solution (1000 mcg/mL)
Drug class: Vitamins

Usage of Cyanocobalamin injection

Cyanocobalamin is used to treat vitamin B12 deficiency in people with pernicious anemia and other conditions.

Cyanocobalamin may also be used for purposes not listed in this medication guide.

Cyanocobalamin injection side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Cyanocobalamin may cause serious side effects. Call your doctor at once if you have:

heart problems--swelling, rapid weight gain, feeling short of breath;

fluid build-up in or around the lungs--pain when you breathe, feeling short of breath while lying down, wheezing, gasping for breath, cough with foamy mucus, cold and clammy skin, anxiety, rapid heartbeats; or

low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.

Common side effects of cyanocobalamin may include:

diarrhea; or

swelling anywhere in your body.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Cyanocobalamin injection

You should not use this medicine if you are allergic to cyanocobalamin or cobalt, or if you have Leber's disease (an inherited form of vision loss). Cyanocobalamin can lead to optic nerve damage (and possibly blindness) in people with Leber's disease.

Tell your doctor if you have ever had:

eye problems or Leber's disease (in you or a family member);

kidney or liver disease;

iron or folic acid deficiency;

any type of infection; or

if you are receiving any medication or treatment that affects bone marrow.

Tell your doctor if you are pregnant or breastfeeding. Your dose needs may be different during pregnancy or while you are nursing.

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How to use Cyanocobalamin injection

Usual Adult Dose for Pernicious Anemia:

Initial dose: 100 mcg intramuscularly or deep subcutaneous once a day for 6 to 7 daysIf clinical improvement and reticulocyte response is seen from the above dosing:-100 mcg every other day for 7 doses, then:-100 mcg every 3 to 4 days for 2 to 3 weeks, then:Maintenance dose: 100 to 1000 mcg monthlyDuration of therapy: LifeComments:-Administer concomitant folic acid if needed.-Chronic treatment should be done with an oral preparation in patients with normal intestinal absorption.

Usual Adult Dose for B12 Nutritional Deficiency:

25 to 2000 mcg orally daily

Usual Adult Dose for Schilling Test:

1000 mcg intramuscularly is the flushing dose

Usual Pediatric Dose for B12 Nutritional Deficiency:

0.5 to 3 mcg daily

Warnings

You should not use cyanocobalamin if you are allergic to cobalt, or if you have Leber's disease.

What other drugs will affect Cyanocobalamin injection

Other drugs may affect cyanocobalamin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Disclaimer

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