Cyanocobalamin nasal
Generic name: Cyanocobalamin (nasal)
Brand names: Nascobal
Dosage form: nasal spray (500 mcg/0.1 mL)
Drug class:
Vitamins
Usage of Cyanocobalamin nasal
Cyanocobalamin nasal (for use in the nose) is used to treat vitamin B12 deficiency in people with pernicious anemia and other conditions.
Cyanocobalamin nasal is usually given after treatment with an injection form of cyanocobalamin.
Cyanocobalamin nasal may also be used for purposes not listed in this medication guide.
Cyanocobalamin nasal side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have :
Common side effects of cyanocobalamin may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Cyanocobalamin nasal
You should not use this medicine if you are allergic to cyanocobalamin or cobalt, or if you have Leber's disease (an inherited form of vision loss). Cyanocobalamin can lead to optic nerve damage (and possibly blindness) in people with Leber's disease.
Tell your doctor if you have ever had:
Tell your doctor if you are pregnant or breast-feeding. Your dose needs may be different during pregnancy or while you are nursing a baby.
Cyanocobalamin nasal is not approved for use by anyone younger than 18 years old.
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How to use Cyanocobalamin nasal
Usual Adult Dose for Pernicious Anemia:
Initial dose: 100 mcg intramuscularly or deep subcutaneous once a day for 6 to 7 daysIf clinical improvement and reticulocyte response is seen from the above dosing:-100 mcg every other day for 7 doses, then:-100 mcg every 3 to 4 days for 2 to 3 weeks, then:Maintenance dose: 100 to 1000 mcg monthlyDuration of therapy: LifeComments:-Administer concomitant folic acid if needed.-Chronic treatment should be done with an oral preparation in patients with normal intestinal absorption.
Usual Adult Dose for B12 Nutritional Deficiency:
25 to 2000 mcg orally daily
Usual Adult Dose for Schilling Test:
1000 mcg intramuscularly is the flushing dose
Usual Pediatric Dose for B12 Nutritional Deficiency:
0.5 to 3 mcg daily
Warnings
You should not use cyanocobalamin if you are allergic to cobalt, or if you have Leber's disease.
What other drugs will affect Cyanocobalamin nasal
Other drugs may affect cyanocobalamin nasal, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
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