Cycloset

Generic name: Bromocriptine

Usage of Cycloset

Cycloset tablets contain micronized bromocriptine in a quick release formulation.

Cycloset is used together with diet and exercise to improve blood sugar control in adults with type 2 type 2 diabetes mellitus.

Cycloset is not for treating type 1 diabetes.

This medication guide provides information about the Cycloset brand of bromocriptine. Parlodel is another brand of bromocriptine that is not covered in this medication guide.

Cycloset side effects

Get emergency medical help if you have signs of an allergic reaction to Cycloset: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

severe drowsiness; or

a light-headed feeling, like you might pass out.

You may have increased sexual urges, unusual urges to gamble, or other intense urges while taking this medicine. Talk with your doctor if this occurs.

Common Cycloset side effects may include:

dizziness, feeling tired;

nausea, vomiting; or

headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Cycloset

You should not use Cycloset if you are allergic to bromocriptine or to an ergot medicine (dihydroergotamine, ergotamine, ergonovine, methylergonovine).

You should not use Cycloset if:

you are breastfeeding;

you had a baby recently;

you have migraine headaches that cause you to faint; or

you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

To make sure Cycloset is safe for you, tell your doctor if you have:

high or low blood pressure, heart disease, or a heart attack;

liver or kidney disease;

a tumor of the pituitary gland;

a stomach ulcer, stomach or intestinal bleeding; or

mental illness or psychosis.

Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

Do not breastfeed while using this medicine.

How to use Cycloset

Usual Adult Dose for Diabetes Type 2:

Initial: 0.8 mg orally once a day -Increase in increments of 0.8 mg weekly as tolerated Maintenance: 1.6 to 4.8 mg orally once a day Maximum Dose: 4.8 mg/day Dose should be taken within 2 hours of waking in the morning with food Concomitant Administration with CYP450 3A4 inhibitors: -Moderate CYP450 3A4 inhibitors (e.g., erythromycin): Do not exceed 1.6 mg/day -Strong CYP450 3A4 inhibitors (e,g., azole antimycotics, HIV protease inhibitors): Avoid concomitant use and ensure adequate washout of strong CYP450 3A4 inhibitors before initiating therapy Comments: -Not for the treatment of type 1 diabetes mellitus or diabetic ketoacidosis -Limited efficacy data in combination with thiazolidinediones -Efficacy has not been confirmed in combination with insulin Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Warnings

You should not use Cycloset if you have migraine headaches that cause you to faint, if you are in a state of diabetic ketoacidosis, or if you recently had a baby.

Do not breastfeed.

Tell your doctor right away if you become pregnant while taking Cycloset.

What other drugs will affect Cycloset

Cycloset can make certain migraine headache medicines less effective when taken at the same time. Avoid taking Cycloset within 6 hours before or 6 hours after you take an ergot headache medicine (such as dihydroergotamine, ergotamine, ergonovine, methylergonovine).

Tell your doctor about all your current medicines. Many drugs can interact with bromocriptine, especially medicine to treat:

type 2 diabetes;

headaches;

psychotic conditions such as bipolar disorder or schizophrenia;

Parkinson's disease;

high blood levels of a hormone called prolactin;

restless leg syndrome; or

acromegaly (too much growth hormone).

This list is not complete and many other drugs may interact with bromocriptine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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