Dapagliflozin and metformin
Generic name: Dapagliflozin And Metformin
Brand names: Xigduo XR
Dosage form: oral tablet, extended release (10 mg-1000 mg; 10 mg-500 mg; 2.5 mg-1000 mg; 5 mg-1000 mg; 5 mg-500 mg)
Drug class:
Antidiabetic combinations
Usage of Dapagliflozin and metformin
Dapagliflozin and metformin is a combination medicine used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. dapagliflozin and metformin is not for treating type 1 diabetes.
Dapagliflozin and metformin is also used to lower the risk of needing to be in the hospital for heart failure in adults with type 2 diabetes who also have heart disease.
Dapagliflozin and metformin is also used to reduce the risk of worsening kidney disease and death due to heart problems, and the need to be in the hospital for heart failure in adults with type 2 diabetes who also have chronic kidney disease.
Dapagliflozin and metformin may also be used for purposes not listed in this medication guide.
Dapagliflozin and metformin side effects
Get emergency medical help if you have signs of an allergic Reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Seek medical attention right away if you have signs of a genital infection (penis or vagina): burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, not feeling well. These symptoms may get worse quickly.
Dapagliflozin and metformin may cause serious side effects. Call your doctor at once if you have:
Side effects may be more likely to occur in older adults.
Common side effects of dapagliflozin and metformin may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Dapagliflozin and metformin
You should not use this medicine if you are allergic to dapagliflozin (Farxiga) or metformin, or if you have
If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking dapagliflozin and metformin.
Tell your doctor if you have ever had:
You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.
Follow your doctor's instructions about using this medicine if you are pregnant. Blood sugar control is very important during pregnancy, and your dose needs may be different during each trimester.
Tell your doctor right away if you become pregnant. You should not use dapagliflozin and metformin during the second or third trimester of pregnancy.
Metformin may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.
You should not breastfeed while using this medicine.
Dapagliflozin and metformin is not approved for use by anyone younger than 18 years old.
Relate drugs
- Actoplus Met
- Actoplus Met XR
- Alogliptin and metformin
- Alogliptin and pioglitazone
- Avandamet
- Avandaryl
- Canagliflozin and metformin
- Dapagliflozin and metformin
- Dapagliflozin and saxagliptin
- Duetact
- Empagliflozin and linagliptin
- Empagliflozin and metformin
- Empagliflozin, linagliptin, and metformin
- Ertugliflozin and metformin
- Ertugliflozin and sitagliptin
- Glimepiride and pioglitazone
- Glipizide and metformin
- Glucovance
- Glyburide and metformin
- Glyxambi
- Insulin degludec and liraglutide
- Insulin glargine and lixisenatide
- Invokamet
- Invokamet XR
- Janumet
- Janumet XR
- Jentadueto
- Jentadueto XR
- Kazano
- Kombiglyze XR
- Linagliptin and metformin
- Metaglip
- Metformin and pioglitazone
- Metformin and saxagliptin
- Metformin and sitagliptin
- Oseni
- Pioglitazone and glimepiride
- Pioglitazone and metformin
- PrandiMet
- Qtern
- Repaglinide and metformin
- Rosiglitazone and glimepiride
- Rosiglitazone and metformin
- Saxagliptin and dapagliflozin
- Saxagliptin and metformin
- Segluromet
- Sitagliptin and metformin
- Soliqua
- Soliqua 100/33
- Steglujan
- Synjardy
- Synjardy XR
- Trijardy XR
- Xigduo XR
- Xultophy
How to use Dapagliflozin and metformin
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Take with food to prevent an upset stomach.
Swallow the tablet whole and do not crush, chew, or break it.
You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).
Your doctor may prescribe a Glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.
Also watch for signs of high blood sugar (hyperglycemia) such as increased thirst or urination.
Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking dapagliflozin and metformin, which can lead to severely low blood pressure or a serious electrolyte imbalance.
If you need surgery or medical tests, tell any doctor who treats you that you are using dapagliflozin and metformin.
This medicine is only part of a treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.
Your kidney function may need to be checked during treatment with dapagliflozin and metformin.
Your doctor may have you take extra vitamin B12 while you are taking dapagliflozin and metformin. Take only the amount of vitamin B12 that your doctor has prescribed.
Store at room temperature, away from moisture and heat.
Warnings
You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.
In rare cases, dapagliflozin and metformin can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don't feel well.
What other drugs will affect Dapagliflozin and metformin
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may affect dapagliflozin and metformin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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