Darifenacin

Generic name: Darifenacin
Brand names: Enablex
Dosage form: oral tablet, extended release (15 mg; 7.5 mg)
Drug class: Urinary antispasmodics

Usage of Darifenacin

Darifenacin reduces muscle spasms of the bladder and urinary tract.

Darifenacin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage).

Darifenacin may also be used for purposes not listed in this medication guide.

Darifenacin side effects

Get emergency medical help if you have any of these signs of an allergic Reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Darifenacin may cause serious side effects. Stop using darifenacin and call your doctor at once if you have:

severe stomach pain or constipation;

confusion, hallucinations;

little or no urinating;

pain or burning when you urinate; or

signs of dehydration--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin.

Common side effects of darifenacin may include:

nausea, indigestion;

constipation;

headache, dizziness;

dry mouth; or

blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Darifenacin

You should not take darifenacin if you are allergic to it, or if you have:

untreated or uncontrolled narrow-angle glaucoma;

a stomach disorder causing delayed emptying; or

if you have trouble emptying your bladder.

To make sure darifenacin is safe for you, tell your doctor if you have:

glaucoma;

liver disease;

ulcerative colitis;

a blockage in your stomach or intestines;

a muscle disorder such as myasthenia gravis; or

if you have very little urine or a weak stream of urine.

FDA pregnancy category C. It is not known whether darifenacin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using darifenacin.

It is not known whether darifenacin passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Relate drugs

How to use Darifenacin

Usual Adult Dose for Urinary Incontinence:

Initial dose: 7.5 mg orally once a dayMaintenance dose: The dosage may be increased to 15 mg orally once a day as early as 2 weeks after starting therapyComments:-This drug may be taken with or without food. -The tablet should be swallowed whole with water and not chewed, divided, or crushed.Use: For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency

Usual Adult Dose for Urinary Frequency:

Warnings

You should not take darifenacin if you are have untreated or uncontrolled narrow-angle glaucoma, a stomach disorder causing delayed emptying, or if you have trouble emptying your bladder.

What other drugs will affect Darifenacin

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with darifenacin, especially:

clarithromycin;

Flecainide;

thioridazine;

an antidepressant--amitriptyline, clomipramine, Desipramine, doxepin, Imipramine, Nefazodone, nortriptyline;

antifungal medicine--itraconazole, ketoconazole; or

HIV or AIDS medicine--Nelfinavir, ritonavir.

This list is not complete. Other drugs may interact with darifenacin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.