Dasiglucagon

Generic name: Dasiglucagon
Dosage form: subcutaneous solution (0.6 mg/0.6 mL)
Drug class: Glucose elevating agents

Usage of Dasiglucagon

DasiGlucagon is used to treat very low blood sugar (severe hypoglycemia) in adults and children at least 6 years old.

Dasiglucagon may also be used for purposes not listed in this medication guide.

Dasiglucagon side effects

Get emergency medical help if you have signs of an allergic reaction: hives; feeling light-headed; difficulty breathing; fast or slow heartbeat; swelling of your face, lips, tongue, or throat.

Dasiglucagon may cause serious side effects. Call your doctor at once if you have:

  • severe headache, blurred vision, pounding in your neck or ears; or
  • new or ongoing low blood sugar--headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky.
  • Common side effects of dasiglucagon may include:

  • nausea, vomiting, diarrhea;
  • headache;
  • pain where an injection was given.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Dasiglucagon

    You should not use dasiglucagon if you are allergic to it, or if you have:

  • a tumor of the pancreas (insulinoma); or
  • a tumor of the adrenal gland (pheochromocytoma).
  • Tell your doctor if you have:

  • any tumor of the pancreas;
  • chronic low blood sugar;
  • adrenal gland problems;
  • a latex allergy; or
  • if you have not recently eaten on a regular basis.
  • Do not give dasiglucagon to a child without medical advice.

    Tell your doctor if you are pregnant or breastfeeding.

    Dasiglucagon is not expected to harm an unborn baby, but quickly treating hypoglycemia would outweigh any risks posed by using dasiglucagon.

    In an emergency situation it may not be possible to tell your caregivers if you are pregnant or breast-feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.

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    How to use Dasiglucagon

    Usual Adult Dose for Hypoglycemia:

    0.6 mg suBCUTAneously once into lower abdomen, buttocks, thigh, or outer upper armIf there has been no response after 15 minutes, a second 0.6 mg dose may be administered Comments:-Patients/caregivers should be familiar with instructions for use; this drug should be administered as soon as possible when severe hypoglycemia is recognized. -Call for emergency assistance immediately after administering dose.-Once patient has responded to treatment, oral carbohydrates should be given to restore liver glycogen stores. Use: For the treatment of severe hypoglycemia in patients with diabetes.

    Usual Pediatric Dose for Hypoglycemia:

    6 years or older: 0.6 mg subcutaneously once into lower abdomen, buttocks, thigh, or outer upper armIf there has been no response after 15 minutes, a second 0.6 mg dose may be administeredComments:-Patients/caregivers should be familiar with instructions for use; this drug should be administered as soon as possible when severe hypoglycemia is recognized. -Call for emergency assistance immediately after administering dose.-Once patient has responded to treatment, oral carbohydrates should be given to restore liver glycogen stores. Use: For the treatment of severe hypoglycemia in pediatric patients 6 years or older with diabetes.

    Warnings

    Be sure you and your caregivers know how to give a dasiglucagon injection before you need to use it. Hypoglycemia should be treated as quickly as possible. Having low blood sugar for too long can cause seizure, coma, or death.

    What other drugs will affect Dasiglucagon

    Tell your doctor about all your other medicines, especially:

  • Indomethacin; or
  • warfarin (Coumadin, Jantoven).
  • This list is not complete. Other drugs may affect dasiglucagon, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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