Daytrana Patch

Generic name: Methylphenidate (transdermal)
Brand names: Daytrana
Drug class: CNS stimulants

Usage of Daytrana Patch

Daytrana is a skin patch that is applied to the skin on your hip. The patch contains methylphenidate, a central nervous system (brain) stimulant. Methylphenidate affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control.

Daytrana patches are used to treat attention deficit hyperactivity disorder (ADHD) in people 6 to 17 years old.

Daytrana may help you have better attention and less impulsive and hyperactive behavior. Daytrana is used as part of a total treatment program for ADHD that may also include counseling or other treatments.

Daytrana Patch side effects

Get emergency medical help if you have signs of an allergic reaction to Daytrana: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Daytrana and call your doctor at once if you have:

redness, swelling, blistering, or skin color changes where the skin patch was worn (may also spread to other areas);

blurred vision;

a seizure;

signs of heart problems - chest pain, trouble breathing, feeling like you might pass out;

signs of psychosis - hallucinations (seeing or hearing things that are not real), new behavior problems, aggression, hostility, paranoia;

signs of circulation problems - numbness, pain, cold feeling, unexplained wounds, or skin color changes (pale, red, or blue appearance) in your fingers or toes; or

penis erection that is painful or lasts 4 hours or longer.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.

Methylphenidate can affect growth in children. Your child's height and weight may need to be checked often. Tell your doctor if your child is not growing at a normal rate.

Common Daytrana side effects may include:

dizziness, mood swings;

tics;

nausea, vomiting, stomach pain, loss of appetite, weight loss;

sleep problems (insomnia); or

skin redness, bumps, or itching where a patch was worn.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Daytrana Patch

You should not use Daytrana if you are allergic to methylphenidate (Ritalin, Concerta, Metadate, and others), or if you have:

glaucoma;

tics (muscle twitches);

a personal or family history of Tourette's syndrome;

severe anxiety, tension, or agitation; or

if you have ever had a skin reaction to a Daytrana skin patch.

Stimulants have caused stroke, heart attack, and sudden death in certain people. Tell your doctor if you have:

heart problems or a congenital heart defect;

high blood pressure; or

a family history of heart disease or sudden death.

Do not use Daytrana if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, Selegiline, and tranylcypromine.

Tell your doctor if you also use opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, serious infections, or prevention of nausea and vomiting. An interaction with Daytrana could cause a serious condition called serotonin syndrome.

To make sure Daytrana is safe for you, tell your doctor if you have ever had:

a skin disorder (such as eczema, psoriasis), skin sensitivity to soaps, lotions, cosmetics, or glues;

vitiligo (loss of skin color in patches) in you or a family member;

depression, mental illness, bipolar disorder, psychosis, or suicidal thoughts or actions;

blood circulation problems in your hands or feet;

a seizure;

an abnormal brain wave test (EEG); or

drug or alcohol addiction.

Becoming Dependent on this medicine during pregnancy can cause premature birth or low birth weight. Tell your doctor if you are pregnant or plan to become pregnant. If you are pregnant, your name may be listed on a pregnancy registry to track the effects of>methylphenidate on the baby.

Ask a doctor if it is safe to breastfeed while using Daytrana. If you are breastfeeding, tell your doctor if you notice symptoms in the baby such as agitation, sleep problems, feeding problems, or reduced weight gain.

Daytrana is not approved for use by anyone younger than 6 years old.

Relate drugs

How to use Daytrana Patch

Usual Pediatric Dose for Attention Deficit Disorder:

Apply a Daytrana patch 2 hours before effect is needed and remove 9 hours after application; recommended dose titration schedule: Week 1: Apply 10 mg patch to hip area once a day; remove 9 hours later Week 2: Apply 15 mg patch to hip area once a day; remove 9 hours later Week 3: Apply 20 mg patch to hip area once a day; remove 9 hours later Week 4: Apply 30 mg patch to hip area once a day; remove 9 hours later -Individualize final dose and wear time to needs and response of the patient; patients converting from other formulation of methylphenidate should follow the above titration schedule.

Warnings

Daytrana may cause new or worsening psychosis (unusual thoughts or behavior), especially if you have a history of depression, mental illness, or bipolar disorder.

You should not use Daytrana if you have glaucoma, tics or Tourette's syndrome, or severe anxiety, tension, or agitation. Do not use methylphenidate if you have taken an MAO inhibitor in the past 14 days, including isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Daytrana may be habit-forming. Tell your doctor if you have a history of drug or alcohol addiction. Keep the medication where others cannot get to it. Never share Daytrana patches with another person, especially someone with a history of drug abuse or addiction.

Stimulants have caused stroke, heart attack, and sudden death in people with high blood pressure, heart disease, or a heart defect.

Call your doctor right away if you have: signs of heart problems - chest pain, feeling light-headed or short of breath; or signs of psychosis - paranoia, aggression, new behavior problems, seeing or hearing things that are not real.

What other drugs will affect Daytrana Patch

Tell your doctor about all your other medicines, especially:

an antidepressant;

blood pressure medication;

a blood thinner such as warfarin (Coumadin, Jantoven);

a cold or allergy medicine that contains a decongestant such as pseudoEphedrine or phenylephrine; or

seizure medicine.

This list is not complete. Other drugs may interact with methylphenidate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Disclaimer

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