Dayvigo

Generic name: Lemborexant
Dosage form: oral tablet
Drug class: Miscellaneous anxiolytics , Antineoplastic Agents

Usage of Dayvigo

Dayvigo (Lemborexant) is a sleeping pill that helps people who have trouble falling or staying asleep to sleep better. It helps you fall asleep faster and stay asleep for longer.

Dayvigo belongs to a class of drugs known as orexin antagonists. Dayvigo works by blocking orexin receptors (OX1R and OX2R), which prevents orexin A and B from binding to them. Orexin A and B are part of the orexin neuropeptide signaling system and one of their roles is to promote wakefulness. Blocking them from their receptor binding sites is thought to help suppress the urge to wake up. This class of drugs works differently from benzodiazepines which have been used to treat insomnia for many years.

Dayvigo is a schedule IV federally controlled substance (CIV) because it can be abused or cause Dependence. Selling or giving away Dayvigo may harm others and is against the law.

Dayvigo was first approved by the US Food and Drug Administration in 2019.

Dayvigo side effects

Dayvigo may cause serious side effects, including:

see “Important information" above

temporary inability to move or talk (sleep paralysis) for up to several minutes while you are going to sleep or waking up.

temporary weakness in your legs that can happen during the day or at night.

complex sleep behaviors such as sleep-walking, sleep-driving, preparing and eating food, making phone calls, having sex or doing other activities while not fully awake that you may not remember the next morning. Call your healthcare provider right away if you experience a complex sleep behavior.

worsening depression and suicidal thoughts have happened during treatment with this medication. Call your healthcare provider right away if you have any worsening depression or thoughts of suicide or dying.

The most common side effect of Dayvigo is sleepiness.

These are not all of the possible side effects of this medication. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Dayvigo

Tell your healthcare provider if you are pregnant or plan to become pregnant. It is not known if Dayvigo can harm your unborn baby.

There is a pregnancy registry for women who are exposed to Dayvigo during pregnancy. The purpose of this registry is to collect information about the health of you and your baby. For more information or to participate in the registry, call 1-888-274-2378. Talk with your healthcare provider about the risk to your unborn baby if you take this medication during pregnancy.

Tell your healthcare provider if you are breastfeeding or plan to breastfeed. It is not known if Dayvigo passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment.

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How to use Dayvigo

The recommended dose of Dayvigo is 5 mg taken no more than once per night, immediately before going to bed, with at least 7 hours remaining before the planned time of awakening. The dose may be increased to 10 mg per night if required.

In patients with moderate liver/hepatic impairment the maximum dose of Dayvigo is 5 mg. This medication is not recommended in patients with severe hepatic impairment.

See Full Prescribing Information for further details about Dayvigo dosing.

Warnings

Dayvigo may cause serious side effects including:

Decreased awareness and alertness. The morning after you take this medication, your ability to drive safely and think clearly may be decreased. You may also have sleepiness during the day.

Do not take more than prescribed.

Do not take unless you are able to stay in bed for a full night (at least 7 hours) before you must be active again.

Take right before going to bed.

See “What are the possible side effects of Dayvigo?” below for more information about side effects.

What other drugs will affect Dayvigo

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Taking Dayvigo with certain other medicines can cause serious side effects. Dayvigo may affect the way other medicines work and other medicines may affect the way this medication works.

Do not take with other medicines that can make you sleepy unless your healthcare provider tells you to.

Know the medicines you take. Keep a list of your medicines with you to show your healthcare provider and pharmacist each time you get a new medicine.

Disclaimer

Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.

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