Deflazacort
Generic name: Deflazacort
Brand names: Emflaza
Drug class:
Glucocorticoids
Usage of Deflazacort
Deflazacort is a steroid that is used to treat Duchenne muscular dystrophy in adults and children at least 2 years old.
Deflazacort is not a cure for muscular dystrophy, but deflazacort may improve muscle strength and slow the progression of disability.
Deflazacort may also be used for purposes not listed in this medication guide.
Deflazacort side effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Deflazacort may cause serious side effects. Call your doctor at once if you have:
Deflazacort can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.
Common side effects of deflazacort may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Deflazacort
You should not use deflazacort if you are allergic to it.
Deflazacort should not be given to a child younger than 2 years old. Deflazacort oral suspension (liquid) contains an ingredient that can cause serious side effects or death in very young or premature babies.
Tell your doctor if you have ever had:
You should be current on all vaccines. Tell your doctor if you have recently received a vaccine or if you are scheduled for a booster dose.
Long-term use of steroids may lead to bone loss (osteoporosis), especially if you smoke, if you do not exercise, if you do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis.
Taking deflazacort during early pregnancy may increase the risk of cleft lip and palate in a newborn. Tell your doctor if you are pregnant or plan to become pregnant.
Taking deflazacort at any time during pregnancy may affect adrenal gland hormones in the newborn baby. Tell your doctor if your baby has symptoms such as dry skin, weakness, feeding problems, or vomiting.
It may not be safe to breastfeed while using deflazacort. Ask your doctor about any risk.
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How to use Deflazacort
Usual Adult Dose for Muscular Dystrophy:
Approximately 0.9 mg/kg orally once a dayComments:-If tablets are used, rounding up to the nearest possible dose is recommended.-If the oral suspension is used, rounding up to the nearest tenth of a mL is recommended.-If this drug has been administered for more than a few days, the dosage should be decreased gradually.Use: For the treatment of Duchenne muscular dystrophy (DMD)
Usual Pediatric Dose for Muscular Dystrophy:
2 years or older: Approximately 0.9 mg/kg orally once a dayComments:-If tablets are used, rounding up to the nearest possible dose is recommended.-If the oral suspension is used, rounding up to the nearest tenth of a mL is recommended.-If this drug has been administered for more than a few days, the dosage should be decreased gradually.Use: For the treatment of DMD
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
What other drugs will affect Deflazacort
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
When you start or stop taking deflazacort, your doctor may need to adjust the doses of any other medicines you take on a regular basis.
Many drugs can affect deflazacort. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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