Deucravacitinib

Generic name: Deucravacitinib (due Krav A Sye Ti Nib)
Brand names: Sotyktu
Dosage form: oral tablet (6 mg)
Drug class: Multikinase inhibitors

Usage of Deucravacitinib

Deucravacitinib is used to treat adults with moderate to severe plaque psoriasis.

Deucravacitinib may also be used for purposes not listed in this medication guide.

Deucravacitinib side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Deucravacitinib can cause the breakdown of muscle tissue, which can lead to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark urine.

Also call your doctor at once if you have:

signs of infection--fever, chills, muscle pain, shortness of breath, weight loss, diarrhea or stomach pain, burning when you urinate, feeling very tired, skin warmth or redness, painful skin sores, or coughing up blood.

Common side effects of deucravacitinib may include:

cold symptoms such as stuffy nose, sneezing, sore throat;

cold sores, sores on your gums, tongue or mouth;

folliculitis (redness or crusting around your hair follicles); or

acne.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Deucravacitinib

You should not use deucravacitinib if you are allergic to it.

Tell your doctor if you have ever had:

liver or kidney disease;

hepatitis B or C;

high blood levels of fat (triglycerides);

any type of cancer;

tuberculosis or have been exposed to tuberculosis;

if you have an infection that keeps returning or does not go away;

if you are being treated for an infection;

if you have recently received or are scheduled to receive a vaccine; or

if you have high blood pressure, high cholesterol, diabetes, menopause (women), family history of coronary artery disease, being overweight, or being over 50, or if you smoke.

Tell your doctor if you are pregnant or breastfeeding.

Relate drugs

How to use Deucravacitinib

Usual Adult Dose for Plaque Psoriasis:

6 mg orally once a dayComments:-Limitations of use: This drug is not recommended for use in combination with other potent immunosuppressants.-Prior to treatment initiation, patients should be evaluated for latent or active tuberculosis infection.-The use of live vaccines during therapy with this drug is not advised.Use: For the treatment of adult patients with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy

Warnings

Serious infections may occur during treatment with deucravacitinib. Call your doctor right away if you have signs of infection such as: fever, chills, muscle pain, shortness of breath, weight loss, diarrhea or stomach pain, burning when you urinate, feeling very tired, skin warmth or redness, painful skin sores, or coughing up blood.

What other drugs will affect Deucravacitinib

Other drugs may affect deucravacitinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Disclaimer

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