Dexbrompheniramine, dextromethorphan, and pseudoephedrine

Generic name: Dexbrompheniramine, Dextromethorphan, And Pseudoephedrine
Brand names: M-End DMX
Dosage form: oral liquid (0.667 mg-10 mg-20 mg/5 mL)
Drug class: Upper respiratory combinations

Usage of Dexbrompheniramine, dextromethorphan, and pseudoephedrine

Brompheniramine" href="/drugs/dexbrompheniramine-4064/">Dexbrompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

DexBrompheniramine, dextromethorphan, and pseudoephedrine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

dexbrompheniramine, dextromethorphan, and pseudoephedrine will not treat a cough that is caused by smoking, asthma, or emphysema.

Dexbrompheniramine, dextromethorphan, and pseudoephedrine may also be used for purposes not listed in this medication guide.

Dexbrompheniramine, dextromethorphan, and pseudoephedrine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:

confusion, severe anxiety, hallucinations, tremors;

weak or shallow breathing;

a light-headed feeling, like you might pass out;

fast or pounding heartbeats;

painful or difficult urination, little or no urinating;

pale skin, weakness, easy bruising or bleeding, fever, chills, body aches; or

increased blood pressure--severe headache, buzzing in your ears, chest pain, shortness of breath, uneven heartbeats.

Common side effects of dexbrompheniramine, dextromethorphan, and pseudoephedrine may include:

dizziness, drowsiness, headache;

constipation, upset stomach, loss of appetite;

blurred vision, double vision, dry eyes;

sleep problems (insomnia); or

dry mouth, nose, or throat.

Side effects such as dry mouth, constipation, and confusion may be more likely in older adults.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Dexbrompheniramine, dextromethorphan, and pseudoephedrine

Do not use dexbrompheniramine, dextromethorphan, and pseudoephedrine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

To make sure this medicine is safe for you, tell your doctor if you have:

asthma or COPD, cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;

a blockage in your digestive tract (stomach or intestines);

high blood pressure, heart disease;

liver or kidney disease;

glaucoma;

cough with mucus, or cough caused by emphysema or chronic bronchitis;

enlarged prostate or urination problems;

pheochromocytoma (an adrenal gland tumor);

overactive thyroid; or

if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

FDA pregnancy category C. It is not known whether dexbrompheniramine, dextromethorphan, and pseudoephedrine will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

This medicine can pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

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How to use Dexbrompheniramine, dextromethorphan, and pseudoephedrine

Usual Adult Dose for Cough and Nasal Congestion:

Dexbrompheniramine/dextromethorphan/pseudoephedrine 0.667 mg-10 mg-20 mg/5 mL oral liquid:15 mL orally every 6 hours not to exceed 60 mL daily.

Usual Pediatric Dose for Cough and Nasal Congestion:

Dexbrompheniramine/dextromethorphan/pseudoephedrine 0.667 mg-10 mg-20 mg/5 mL oral liquid:6 to 11 years: 7.5 mL orally every 6 hours not to exceed 30 mL daily12 years or older: 15 mL orally every 6 hours not to exceed 60 mL daily.

Warnings

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

What other drugs will affect Dexbrompheniramine, dextromethorphan, and pseudoephedrine

Tell your doctor about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.

Taking dexbrompheniramine, dextromethorphan, and pseudoephedrine with other drugs that make you sleepy or slow your breathing can worsen these effects. Ask your doctor before taking dexbrompheniramine, dextromethorphan, and pseudoephedrine with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.

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