Dexlansoprazole

Generic name: Dexlansoprazole
Dosage form: oral delayed release capsule (30 mg; 60 mg)
Drug class: Proton pump inhibitors

Usage of Dexlansoprazole

Dexlansoprazole is used to treat heartburn caused by gastroesophageal reflux disease (GERD), and to heal erosive esophagitis (damage to the esophagus from stomach acid).

Dexlansoprazole may also be used for purposes not listed in this medication guide.

Dexlansoprazole side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Dexlansoprazole may cause serious side effects. Call your doctor at once if you have:

severe stomach pain, diarrhea that is watery or bloody;

a seizure (convulsions);

sudden pain or trouble moving your hip, wrist, or back;

kidney problems-- fever, rash, nausea, loss of appetite, joint pain, urinating less than usual, blood in your urine, weight gain;

low magnesium--dizziness, fast or irregular heart rate, tremors (shaking) or jerking muscle movements, feeling jittery, muscle cramps, muscle spasms in your hands and feet, cough or choking feeling; or

new or worsening symptoms of lupus--joint pain, and a skin rash on your cheeks or arms that worsens in sunlight.

Taking dexlansoprazole long-term may cause you to develop stomach growths called fundic gland polyps. Talk with your doctor about this risk.

If you use dexlansoprazole for longer than 3 years, you could develop a vitamin B-12 deficiency. Talk to your doctor about how to manage this condition if you develop it.

Common side effects of dexlansoprazole may include:

nausea, vomiting, stomach pain, gas;

diarrhea;

headache;

mouth pain, sore throat; or

stuffy nose, sinus pain, or other cold symptoms.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Before taking Dexlansoprazole

Heartburn can mimic early symptoms of a heart attack. Get emergency medical help if you have chest pain that spreads to your jaw or shoulder and you feel anxious or light-headed.

You should not take this medicine if you are allergic to dexlansoprazole, or if:

you had breathing problems, kidney problems, or a severe allergic reaction after taking this medicine in the past; or

you also take a medicine that contains rilpivirine (Complera, Edurant, Odefsey).

Tell your doctor if you have ever had:

severe liver disease;

osteoporosis;

low bone mineral density (osteopenia); or

low levels of magnesium in your blood.

You may be more likely to have a broken bone in your hip, wrist, or spine while taking a proton pump inhibitor long-term or more than once per day. Talk with your doctor about ways to keep your bones healthy.

Dexlansoprazole may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Dexlansoprazole is not approved for use by anyone younger than 12 years old.

Relate drugs

How to use Dexlansoprazole

Usual Adult Dose for Erosive Esophagitis:

Healing of Erosive Esophagitis (EE): 60 mg orally once a day-Duration of therapy: Up to 8 weeksMaintenance dose: 30 mg orally once a day-Duration of therapy: Up to 6 monthsComments:-Patients may be given maintenance doses for the relief of heartburn.-Controlled studies for maintenance therapy did not extend beyond 6 months.Uses:-Healing of all grades of EE-Maintenance of healed EE-Relief of heartburn

Usual Adult Dose for Gastroesophageal Reflux Disease:

30 mg orally once a day-Duration of therapy: 4 weeksUse: Treatment of heartburn associated with symptomatic non-erosive gastroesophageal reflux disease (GERD)

Usual Pediatric Dose for Erosive Esophagitis:

12 years and older:Healing of EE: 60 mg orally once a day-Duration of therapy: Up to 8 weeksMaintenance dose: 30 mg orally once a day-Duration of therapy: Up to 6 monthsComments:-Patients may be given maintenance doses for the relief of heartburn.-Controlled studies of maintenance therapy did not extend beyond 16 weeks.Uses:-Healing of all grades of EE-Maintenance of healed EE-Relief of heartburn

Usual Pediatric Dose for Gastroesophageal Reflux Disease:

12 years and older: 30 mg orally once a day-Duration of therapy: 4 weeksUse: Treatment of heartburn associated with symptomatic non-erosive GERD

Warnings

Dexlansoprazole can cause kidney problems. Tell your doctor if you are urinating less than usual, or if you have blood in your urine.

Diarrhea may be a sign of a new infection. Call your doctor if you have diarrhea that is watery or has blood in it.

Dexlansoprazole may cause new or worsening symptoms of lupus. Tell your doctor if you have joint pain and a skin rash on your cheeks or arms that worsens in sunlight.

You may be more likely to have a broken bone while taking dexlansoprazole long term or more than once per day.

What other drugs will affect Dexlansoprazole

Tell your doctor about all your current medicines. Many drugs can affect dexlansoprazole, especially:

methotrexate;

rifampin;

St. John's wort; or

warfarin (Coumadin, Jantoven).

This list is not complete and many other drugs may affect dexlansoprazole. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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