Dexmedetomidine buccal/sublingual
Generic name: Dexmedetomidine (buccal/sublingual)
Brand names: Igalmi
Dosage form: sublingual film (120 mcg; 180 mcg)
Drug class:
Miscellaneous anxiolytics , Antineoplastic Agents
Usage of Dexmedetomidine buccal/sublingual
Dexmedetomidine (buccal/sublingual) is used in adults to treat agitation associated with schizophrenia or bipolar I or II disorder.
The safety and effectiveness of dexmedetomidine (buccal/sublingual) has not been established after 24 hours from the first use.
Dexmedetomidine (buccal/sublingual) may also be used for purposes not listed in this medication guide.
Dexmedetomidine buccal/sublingual side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Dexmedetomidine may cause serious side effects. Call your doctor at once if you have:
Common side effects of dexmedetomidine may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Before taking Dexmedetomidine buccal/sublingual
Tell your doctor if you have ever had:
It is not known if dexmedetomidine (buccal/sublingual) will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
If you are breastfeeding, tell your doctor if you notice irritability in the nursing baby.
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How to use Dexmedetomidine buccal/sublingual
Usual Adult Dose for Sedation:
Intensive Care Unit Sedation: -Initial Dose: Loading dose of 1 mcg/kg IV infusion over 10 minutes.-Maintenance Dose: 0.2 to 0.7 mcg/kg/hour IV infusion; adjust the infusion rate to achieve the desired clinical effect.Procedural Sedation:-Initial Dose (including Awake Fiberoptic Intubation): 1 mcg/kg IV infusion over 10 minutes.-Maintenance Dose: Initiate IV infusion at 0.6 mcg/kg/hour and titrate to achieve the desired clinical effect; doses may range from 0.2 to 1 mcg/kg/hour.Uses: Sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting; sedation of non-intubated patients prior to and/or during surgical and other procedures.
Usual Geriatric Dose for Sedation:
Over Age 65 Years:Intensive Care Unit Sedation: Dose reduction may be required; however, no specific guidelines have been suggested. Procedural Sedation: -Initial Dose: May be omitted or reduced (e.g., 0.5 mcg/kg IV infusion over 10 minutes).-Maintenance Dose: Dose reduction may be required; however, no specific guidelines have been suggested.Uses: Sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting; sedation of non-intubated patients prior to and/or during surgical and other procedures.
Warnings
Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.
What other drugs will affect Dexmedetomidine buccal/sublingual
Dexmedetomidine (buccal/sublingual) can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.
Using dexmedetomidine (buccal/sublingual) with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Other drugs may affect dexmedetomidine (buccal/sublingual), including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
Disclaimer
Every effort has been made to ensure that the information provided by Drugslib.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Drugslib.com information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Drugslib.com does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Drugslib.com's drug information does not endorse drugs, diagnose patients or recommend therapy. Drugslib.com's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.
The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Drugslib.com does not assume any responsibility for any aspect of healthcare administered with the aid of information Drugslib.com provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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