Diclegis

Generic name: Doxylamine And Pyridoxine
Drug class: Miscellaneous antiemetics

Usage of Diclegis

Diclegis is a delayed-release tablet containing a combination of doxylamine and pyridoxine. Doxylamine is an antihistamine that reduces the effects of natural chemical histamine in the body. Pyridoxine is a form of vitamin B (B6).

Diclegis is used to treat nausea and vomiting during pregnancy, sometimes called morning sickness.

Diclegis may also be used for purposes not listed in this medication guide.

Diclegis side effects

Get emergency medical help if you have signs of an allergic reaction to Diclegis: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common Diclegis side effects may include:

  • drowsiness.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Diclegis

    Do not use Diclegis if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

    You should not use this medicine if you are allergic to doxylamine or pyridoxine, or to other antihistamines such as Benadryl or Dramamine.

    Tell your doctor if you have ever had:

  • asthma or other breathing disorder;
  • glaucoma, increased pressure inside your eye;
  • blockage in your digestive tract (stomach or intestines);
  • a stomach ulcer; or
  • bladder obstruction or other urination problems.
  • You should not breast-feed while using Diclegis.

    Diclegis is not approved for use by anyone younger than 18 years old.

    Relate drugs

    How to use Diclegis

    Usual Adult Dose for Nausea/Vomiting:

    During Pregnancy: 2 tablets orally at bedtime Maximum dose: 4 tablets daily Comments: Take daily and not on an as needed basis.

    Warnings

    Do not use Diclegis if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

    What other drugs will affect Diclegis

    Using Diclegis with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety, depression, or seizures.

    Other drugs may affect Diclegis, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

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