Dicyclomine

Generic name: Dicyclomine (oral/injection)
Drug class: Anticholinergics / antispasmodics

Usage of Dicyclomine

Dicyclomine is used to treat functional bowel or irritable bowel syndrome.

Dicyclomine may also be used for purposes not listed in this medication guide.

Dicyclomine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Dicyclomine may cause serious side effects. Call your doctor at once if you have:

  • fast or slow heartbeats, pounding heartbeats or fluttering in your chest;
  • confusion, agitation, hallucinations, unusual thoughts or behavior;
  • problems with memory or speech;
  • problems with balance or muscle movement;
  • diarrhea, severe constipation, or worsening of bowel symptoms;
  • trouble swallowing;
  • bruising, swelling, or pain where a dicyclomine injection was given; or
  • dehydration --dizziness, confusion, feeling very thirsty, less urination or sweating.
  • Confusion and mood or behavior changes may be more likely in older adults.

    Common side effects of dicyclomine may include:

  • drowsiness, dizziness, weakness, nervousness;
  • blurred vision;
  • dry mouth; or
  • nausea.
  • This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

    Before taking Dicyclomine

    You should not use dicyclomine if you are allergic to it, or if you have:

  • glaucoma;
  • a bladder obstruction or other urination problems;
  • a blockage in your digestive tract (stomach or intestines);
  • severe ulcerative colitis;
  • gastroesophageal reflux disease (GERD);
  • a serious heart condition and active bleeding;
  • myasthenia gravis; or
  • if you are breastfeeding a baby.
  • Not approved for use by anyone younger than 18 years old. Dicyclomine should never be given to a child younger than 6 months old.

    Tell your doctor if you have ever had:

  • heart problems or high blood pressure;
  • a stroke;
  • ulcerative colitis;
  • an ileostomy or colostomy;
  • an enlarged prostate; or
  • liver or kidney disease.
  • Older adults may be more sensitive to the effects of dicyclomine.

    Tell your doctor if you are pregnant.

    Do not breastfeed.

    Relate drugs

    How to use Dicyclomine

    Usual Adult Dose for Irritable Bowel Syndrome:

    Oral:Initial dose: 20 mg orally four times a dayMaintenance dose: Up to 40 mg orally four times a day, after one week with initial doseComments:-Discontinue this drug if efficacy is not achieved within 2 weeks or side effects require doses below 80 mg per day.-Documented safety data are not available for doses above 80 mg daily for periods longer than 2 weeks.Intramuscular:10 to 20 mg four times a dayDuration of therapy: 1 or 2 weeks, when patient cannot take oral formComments: Administer injection via IM onlyUses: Treatment of patients with functional bowel/irritable bowel syndrome

    Warnings

    Many drugs can affect dicyclomine. Tell your doctor about all your current medicines.

    What other drugs will affect Dicyclomine

    Using dicyclomine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

    Tell your doctor about all your current medicines. Many drugs can affect dicyclomine, especially:

  • bronchodilator asthma medication;
  • cold or allergy medicine (Benadryl and others);
  • glaucoma medication;
  • heart medication;
  • medicine to treat depression, anxiety, mood disorders, or mental illness;
  • medicine to treat overactive bladder;
  • medicine to treat Parkinson's disease; or
  • medicine to treat stomach problems, motion sickness, or irritable bowel syndrome.
  • This list is not complete and many other drugs may affect dicyclomine. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

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